1. Genes and Genomic Entities
  2. C8G

C8G

complement C8 gamma chain
OMIM: 120930, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green C8G in COVID-19 research


Level 2: Viral research
Version 1.142

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • IUIS Classification February 2018
  • IUIS Classification December 2019
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Complement Deficiencies
  • Complement factor 8 defect
  • Complement component 8 deficiency
  • Disseminated neisserial infections
Red C8G in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 5.3
Latest signed off version: v5.0 (1 May 2024)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Red
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Complement Deficiencies
  • Disseminated neisserial infections
  • Complement component 8 deficiency
  • Complement factor 8 defect
Green C8G in Severe Paediatric Disorders


Version 1.184

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Complement factor 8 defect