IRAK1

interleukin 1 receptor associated kinase 1
OMIM: 300283, Gene2Phenotype

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Green IRAK1 in COVID-19 research Level 2: Viral research Version 1.142	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Green IUIS Classification December 2019 IUIS Classification February 2018 IUIS Classification December 2019 IUIS Classification February 2018 Phenotypes Bacterial infections, X-linked MECP2 deficiency-related syndrome due to a large de novo Xq28 chromosomal deletion encompassing both MECP2 and IRAK1 Defects in Intrinsic and Innate Immunity
Red IRAK1 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 5.3 Latest signed off version: v5.0 (1 May 2024)	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources IUIS Classification December 2019 Expert Review Red IUIS Classification February 2018 Phenotypes Defects in Intrinsic and Innate Immunity Bacterial infections, X-linked MECP2 deficiency-related syndrome due to a large de novo Xq28 chromosomal deletion encompassing both MECP2 and IRAK1
Red IRAK1 in Intellectual disability Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 6.13 Latest signed off version: v6.0 (1 May 2024) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	Unknown	Sources Expert Review Red UKGTN Phenotypes Lubs X-Linked Mental Retardation Syndrome MRXSL