ITK

IL2 inducible T-cell kinase
OMIM: 186973, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green ITK in Haematological malignancies for rare disease Level 3: Tumour syndromes Level 2: Tumour syndromes Version 1.18	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Curated sources Phenotypes Class: miscellaneous Lymphoproliferative syndrome 1 Hodgkins lymphoma
Green ITK in COVID-19 research Level 2: Viral research Version 1.142	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH GOSH PID v.8.0 NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Combined B and T cell defect v1.12 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Combined B and T cell defect v1.12 Phenotypes EBV associated B cell lymphoproliferation, lymphoma, Nl or low IgG Combined immunodeficiency Diseases of Immune Dysregulation ITK deficiency (HLH phenotype) EBV viraemia, HLH Lymphoproliferative syndrome 1
Green ITK in Primary immunodeficiency or monogenic inflammatory bowel disease Version 5.3 Latest signed off version: v5.0 (1 May 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Combined B and T cell defect v1.12 Phenotypes Lymphoproliferative syndrome 1 Combined immunodeficiency ITK deficiency (HLH phenotype) EBV viraemia, HLH EBV associated B cell lymphoproliferation, lymphoma, Nl or low IgG Diseases of Immune Dysregulation
Green ITK in Haematological malignancies cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 4.5 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Curated sources Phenotypes Class: miscellaneous Lymphoproliferative syndrome 1 Hodgkins lymphoma
Green ITK in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Lymphoproliferative syndrome 1, 613011