MET

MET proto-oncogene, receptor tyrosine kinase
OMIM: 164860, Gene2Phenotype

9 panels

Panel Reviews Mode of inheritance Details
9 panels
Green MET in Renal cancer pertinent cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 1.2

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Renal cancer
Green MET in Adult solid tumours for rare disease

Level 3: Tumour syndromes
Level 2: Tumour syndromes
Version 1.40

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert list
  • Expert Review Green
Phenotypes
  • Renal cell cancer, papillary carcinoma
Red MET in COVID-19 research


Level 2: Viral research
Version 1.142

review Not set
Sources
  • OMIM
Green MET in Inherited renal cancer


Version 1.27
Latest signed off version: v1.2 (4 Mar 2020)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert List
  • UKGTN
Phenotypes
  • Renal cell carcinoma, papillary, 1, familial and somatic, OMIM:605074
  • Papillary renal cell carcinoma, MONDO:0017884
Amber MET in Autism


Version 0.36

review Not set
Sources
  • Expert Review Amber
  • SFARI
Green MET in Adult solid tumours cancer susceptibility

Level 3: Pertinent cancer susceptibility gene panel
Level 2: Cancer Programme
Version 2.29
Latest signed off version: v2.2 (18 Feb 2020)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • NHS GMS
  • Expert Review Green
  • Expert list
Phenotypes
  • Renal cell cancer, papillary carcinoma
Amber MET in Monogenic hearing loss

Level 3: Non-syndromic hearing loss
Level 2: Hearing and ear disorders
Version 4.41
Latest signed off version: v4.39 (1 May 2024)

Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Expert list
    Phenotypes
    • Deafness, autosomal recessive 97 OMIM:616705
    • autosomal recessive nonsyndromic deafness 97 MONDO:0014739
    Red MET in Intellectual disability

    Level 3: Neurodevelopmental disorders
    Level 2: Neurology and neurodevelopmental disorders
    Version 6.13
    Latest signed off version: v6.0 (1 May 2024)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders
  • review Not set
    Sources
    • Victorian Clinical Genetics Services
    Red MET in Primary lymphoedema

    Level 3: Lymphatic Disorders
    Level 2: Cardiovascular disorders
    Version 3.11
    Latest signed off version: v3.0 (30 Nov 2022)

    review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert list