1. Genes and Genomic Entities
  2. SCN2B

SCN2B

sodium voltage-gated channel beta subunit 2
OMIM: 601327, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Red SCN2B in Short QT syndrome


Version 3.12
Latest signed off version: v3.11 (1 May 2024)

Component of the following Super Panels:

  • Cardiac arrhythmias
  • Sudden unexplained death or survivors of a cardiac event
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review Not set
    Sources
    • Brugada syndrome (Version 1.7)
    Red SCN2B in Brugada syndrome and cardiac sodium channel disease

    Level 3: Cardiac arrhythmia
    Level 2: Cardiovascular disorders
    Version 3.10
    Latest signed off version: v3.9 (1 May 2024)

    Component of the following Super Panels:

  • Cardiac arrhythmias
  • Sudden unexplained death or survivors of a cardiac event
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    • South West GLH
    • Oxford Medical Genetics Laboratory
    Phenotypes
    • Brugada syndrome, MONDO:0015263
    Red SCN2B in Early onset or syndromic epilepsy

    Level 3: Inherited Epilepsy Syndromes
    Level 2: Neurology and neurodevelopmental disorders
    Version 5.10
    Latest signed off version: v5.0 (1 May 2024)

    Component of the following Super Panels:

  • Paediatric disorders
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review Not set
    Sources
    • Wessex and West Midlands GLH
    • NHS GMS
    • Expert Review Red
    • Expert