1. Genes and Genomic Entities
  2. ZEB1

ZEB1

zinc finger E-box binding homeobox 1
OMIM: 189909, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green ZEB1 in Corneal abnormalities

Level 3: Anterior segment abnormalities
Level 2: Ophthalmological disorders
Version 1.13

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • GDL Corneal Abnormalities panel
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Corneal dystrophy, posterior polymorphous, 3, 609141
  • Posterior polymorphous corneal dystrophy 3 (PPCD3), AD
  • Fuchs endothelial corneal dystrophy
Green ZEB1 in Corneal dystrophy


Version 3.10
Latest signed off version: v3.2 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • Corneal dystrophy, posterior polymorphous, 3 609141
  • Corneal dystrophy, Fuchs endothelial, 6 613270
Red ZEB1 in DDG2P


Version 4.3
Latest signed off version: v4.0 (1 May 2024)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • DD-Gene2Phenotype
    • Expert Review Red
    Phenotypes
    • CORNEAL DYSTROPHY FUCHS ENDOTHELIAL TYPE 6 613270
    • POSTERIOR POLYMORPHOUS CORNEAL DYSTROPHY TYPE 3 609141
    Red ZEB1 in Structural eye disease


    Version 3.79
    Latest signed off version: v3.0 (22 Mar 2023)

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • NHS GMS
    Phenotypes
    • Corneal dystrophy, Fuchs endothelial, 6, 613270
    • Corneal dystrophy, posterior polymorphous, 3, 609141