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{
"count": 216020,
"next": "https://panelapp.genomicsengland.co.uk/api/v1/activities/?format=api&page=6",
"previous": "https://panelapp.genomicsengland.co.uk/api/v1/activities/?format=api&page=4",
"results": [
{
"created": "2024-05-03T20:32:11.606930Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to SEC61A1.\nSource Expert Review Green was added to SEC61A1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "SEC61A1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:11.290163Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to SAMD9L.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "SAMD9L",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:10.790367Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to RELA.\nSource Expert Review Green was added to RELA.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "RELA",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:10.056780Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to REL.\nSource Expert Review Green was added to REL.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "REL",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:09.625315Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to RANBP2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "RANBP2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:09.270038Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to PTPN2.\nSource Expert Review Green was added to PTPN2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PTPN2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:08.895232Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to PSMB10.\nSource Expert Review Green was added to PSMB10.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PSMB10",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:08.541545Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to POLD1.\nSource Expert Review Green was added to POLD1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "POLD1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:08.216280Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Mode of inheritance for gene OTULIN was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "OTULIN",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:07.880208Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to NLRP1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "NLRP1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:07.443877Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to NFAT5.\nSource Expert Review Green was added to NFAT5.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "NFAT5",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:06.819497Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to MECOM.\nSource Expert Review Green was added to MECOM.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "MECOM",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:06.500361Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to MCTS1.\nSource Expert Review Green was added to MCTS1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "MCTS1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:06.125774Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to LYN.\nSource Expert Review Green was added to LYN.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "LYN",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:05.650593Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to JAK1.\nSource Expert Review Green was added to JAK1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "JAK1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:05.287000Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to IRF4.\nSource Expert Review Green was added to IRF4.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "IRF4",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:04.905085Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to IRF2BP2.\nSource Expert Review Green was added to IRF2BP2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "IRF2BP2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:04.607200Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to IL23R.\nSource Expert Review Green was added to IL23R.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "IL23R",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:04.307652Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to HYOU1.\nSource Expert Review Green was added to HYOU1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HYOU1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:03.978762Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to HMOX1.\nSource Expert Review Green was added to HMOX1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HMOX1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:03.287698Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to DUT.\nSource Expert Review Green was added to DUT.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "DUT",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:02.809355Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to DOCK11.\nSource Expert Review Green was added to DOCK11.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "DOCK11",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:02.342446Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to DIAPH1.\nSource Expert Review Green was added to DIAPH1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "DIAPH1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:01.897320Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Amber was added to DCLRE1B.\nRating Changed from Green List (high evidence) to Amber List (moderate evidence)",
"entity_name": "DCLRE1B",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:01.369327Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to CXCR2.\nSource Expert Review Green was added to CXCR2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "CXCR2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:00.762598Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to CR2.\nSource Expert Review Green was added to CR2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "CR2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:32:00.284392Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to CD81.\nSource Expert Review Green was added to CD81.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "CD81",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:31:59.790373Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to CD4.\nSource Expert Review Green was added to CD4.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "CD4",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:31:59.027317Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to CBLB.\nSource Expert Review Green was added to CBLB.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "CBLB",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:31:58.609831Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to ARPC5.\nSource Expert Review Green was added to ARPC5.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "ARPC5",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:31:58.262778Z",
"panel_name": "Primary immunodeficiency or monogenic inflammatory bowel disease",
"panel_id": 398,
"panel_version": "5.2",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Mode of inheritance for gene AICDA was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal",
"entity_name": "AICDA",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:26:49.676484Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.9",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q4_23_promote_green was removed from gene: HBG2.",
"entity_name": "HBG2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:26:36.139723Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.9",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q4_23_promote_green was removed from gene: HBG1.",
"entity_name": "HBG1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:26:12.318161Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.9",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q4_23_promote_green was removed from gene: HBA2.",
"entity_name": "HBA2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:25:50.285806Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.9",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: HBG2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
"entity_name": "HBG2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:25:50.266731Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.9",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: HBG1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "HBG1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:25:50.248483Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.9",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: HBA2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal",
"entity_name": "HBA2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:24:39.225933Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.8",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to HBG2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HBG2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:24:39.146841Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.8",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to HBG1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HBG1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:24:39.070670Z",
"panel_name": "Thalassaemia and other haemoglobinopathies",
"panel_id": 1397,
"panel_version": "1.8",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to HBA2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HBA2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:17:21.101385Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.9",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q4_23_promote_green was removed from gene: HBG2.",
"entity_name": "HBG2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:16:59.826477Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.9",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q4_23_promote_green was removed from gene: HBG1.",
"entity_name": "HBG1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:16:39.619578Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.9",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q4_23_promote_green was removed from gene: HBA2.",
"entity_name": "HBA2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:16:07.618106Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.9",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: HBG2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
"entity_name": "HBG2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:16:07.598644Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.9",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: HBG1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
"entity_name": "HBG1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:16:07.580565Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.9",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: HBA2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal",
"entity_name": "HBA2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:14:03.203462Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.8",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to HBG2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HBG2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:14:03.125087Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.8",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to HBG1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HBG1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:14:03.035930Z",
"panel_name": "Haemoglobinopathy trait or carrier testing",
"panel_id": 1342,
"panel_version": "1.8",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to HBA2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "HBA2",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:12:00.709184Z",
"panel_name": "Neonatal diabetes",
"panel_id": 293,
"panel_version": "4.6",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag to_be_confirmed_NHSE was removed from gene: ONECUT1.",
"entity_name": "ONECUT1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:11:38.933031Z",
"panel_name": "Neonatal diabetes",
"panel_id": 293,
"panel_version": "4.6",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag to_be_confirmed_NHSE was removed from gene: CNOT1.",
"entity_name": "CNOT1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:10:23.759189Z",
"panel_name": "Neonatal diabetes",
"panel_id": 293,
"panel_version": "4.6",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: ONECUT1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal",
"entity_name": "ONECUT1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:10:23.732396Z",
"panel_name": "Neonatal diabetes",
"panel_id": 293,
"panel_version": "4.6",
"user_name": "Sarah Leigh",
"item_type": "entity",
"text": "reviewed gene: CNOT1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
"entity_name": "CNOT1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:09:53.934287Z",
"panel_name": "Neonatal diabetes",
"panel_id": 293,
"panel_version": "4.5",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to ONECUT1.\nSource Expert Review Green was added to ONECUT1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "ONECUT1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:09:53.792757Z",
"panel_name": "Neonatal diabetes",
"panel_id": 293,
"panel_version": "4.5",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source NHS GMS was added to CNOT1.\nSource Expert Review Green was added to CNOT1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "CNOT1",
"entity_type": "gene"
},
{
"created": "2024-05-03T20:00:59.590273Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: AKT2.\nTag Q3_23_NHS_review was removed from gene: AKT2.",
"entity_name": "AKT2",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:59:51.372471Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "WRN",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:59:19.124152Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: WRN.\nTag Q3_23_NHS_review was removed from gene: WRN.",
"entity_name": "WRN",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:58:59.782756Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: PSMB8.\nTag Q3_23_NHS_review was removed from gene: PSMB8.",
"entity_name": "PSMB8",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:58:34.861327Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PSMB8",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:58:13.980144Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PSMB4",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:57:55.794025Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: PSMB4.\nTag Q3_23_NHS_review was removed from gene: PSMB4.",
"entity_name": "PSMB4",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:57:37.843765Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: POC1A.\nTag Q3_23_NHS_review was removed from gene: POC1A.",
"entity_name": "POC1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:57:27.677051Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "POC1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:57:06.028456Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toMONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.",
"entity_name": "PIK3R1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:56:45.760076Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: PIK3R1.\nTag Q3_23_NHS_review was removed from gene: PIK3R1.",
"entity_name": "PIK3R1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:56:19.691598Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PCYT1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:56:01.371554Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: PCYT1A.\nTag Q3_23_NHS_review was removed from gene: PCYT1A.",
"entity_name": "PCYT1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:55:43.926607Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: PCNT.\nTag Q3_23_NHS_review was removed from gene: PCNT.",
"entity_name": "PCNT",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:55:27.790610Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PCNT",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:54:57.877074Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: MFN2.\nTag Q3_23_NHS_review was removed from gene: MFN2.",
"entity_name": "MFN2",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:54:39.275795Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "MFN2",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:54:11.550610Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toMONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.",
"entity_name": "EPHX1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:53:46.694799Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: EPHX1.\nTag Q3_23_NHS_review was removed from gene: EPHX1.",
"entity_name": "EPHX1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:53:28.315716Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: BLM.\nTag Q3_23_NHS_review was removed from gene: BLM.",
"entity_name": "BLM",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:53:15.553751Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "BLM",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:52:51.273094Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Tag Q3_23_promote_green was removed from gene: ALMS1.\nTag Q3_23_NHS_review was removed from gene: ALMS1.",
"entity_name": "ALMS1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:52:36.304156Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "changed review comment from: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.; to: The rating of this gene has been updated to Green and the mode of inheritance set to BIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "ALMS1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:35.052683Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: WRN: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "WRN",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:35.032583Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: PSMB8: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PSMB8",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:35.003711Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: PSMB4: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PSMB4",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.984215Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: POC1A: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "POC1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.966399Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: PIK3R1: The rating of this gene has been updated toGreenand the mode of inheritance set toMONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.",
"entity_name": "PIK3R1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.949605Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: PCYT1A: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PCYT1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.933262Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: PCNT: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "PCNT",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.911499Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: MFN2: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "MFN2",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.891740Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: EPHX1: The rating of this gene has been updated toGreenand the mode of inheritance set toMONOALLELIC, autosomal or pseudoautosomal, NOT imprinted following NHS Genomic Medicine Service approval.",
"entity_name": "EPHX1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.865686Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: BLM: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "BLM",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.847659Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "commented on gene: ALMS1: The rating of this gene has been updated toGreenand the mode of inheritance set toBIALLELIC, autosomal or pseudoautosomal following NHS Genomic Medicine Service approval.",
"entity_name": "ALMS1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:34.829867Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.52",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "edited their review of gene: AKT2: Added comment: After NHS Genomic Medicine Service consideration, the rating of this gene has not been changed and remains amber. Comment from GMS: 'Should be amber. Another family is needed for AKT2 for this to be upgraded to Green. The two variants used as evidence, p.Arg467Trp and p.Arg208Lys, far too common in gnomAD to be causing a rare AD disorder.'; Changed rating: AMBER",
"entity_name": "AKT2",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:16.793399Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to WRN.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "WRN",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:16.645131Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to PSMB8.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PSMB8",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:16.321086Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to PSMB4.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PSMB4",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:16.045479Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to POC1A.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "POC1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:15.841619Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to PIK3R1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PIK3R1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:15.664438Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to PCYT1A.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PCYT1A",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:15.486534Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to PCNT.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "PCNT",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:15.391734Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to MFN2.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "MFN2",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:15.272353Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to EPHX1.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "EPHX1",
"entity_type": "gene"
},
{
"created": "2024-05-03T19:50:14.984258Z",
"panel_name": "Lipodystrophy - childhood onset",
"panel_id": 546,
"panel_version": "4.51",
"user_name": "Achchuthan Shanmugasundram",
"item_type": "entity",
"text": "Source Expert Review Green was added to BLM.\nRating Changed from Amber List (moderate evidence) to Green List (high evidence)",
"entity_name": "BLM",
"entity_type": "gene"
}
]
}