GET /api/v1/activities/?page=2
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

{
    "count": 177481,
    "next": "https://panelapp.genomicsengland.co.uk/api/v1/activities/?page=3",
    "previous": "https://panelapp.genomicsengland.co.uk/api/v1/activities/",
    "results": [
        {
            "created": "2021-11-30T14:52:37.573729Z",
            "panel_name": "Malformations of cortical development",
            "panel_id": 96,
            "panel_version": "2.100",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: eno1 has been classified as Red List (Low Evidence).",
            "entity_name": "ENO1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T14:51:51.777620Z",
            "panel_name": "Malformations of cortical development",
            "panel_id": 96,
            "panel_version": "2.99",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: ENO1 were changed from Polymicrogyria to Polymicrogyria, MONDO:0000087",
            "entity_name": "ENO1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:55:16.120798Z",
            "panel_name": "Hereditary neuropathy NOT PMP22 copy number",
            "panel_id": 846,
            "panel_version": "1.67",
            "user_name": "Evan Reid",
            "item_type": "entity",
            "text": "edited their review of gene: HEXB: Changed rating: GREEN",
            "entity_name": "HEXB",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:54:24.468130Z",
            "panel_name": "Hereditary neuropathy NOT PMP22 copy number",
            "panel_id": 846,
            "panel_version": "1.67",
            "user_name": "Evan Reid",
            "item_type": "entity",
            "text": "gene: HEXA was added\ngene: HEXA was added to Hereditary neuropathy NOT PMP22 copy number. Sources: Literature\nMode of inheritance for gene: HEXA was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: HEXA were set to PMID: 28739864; 18642377\nPenetrance for gene: HEXA were set to Complete\nReview for gene: HEXA was set to GREEN\nAdded comment: Both HEXA and HEXB autosomal recessive mutations can be associated with a late onset motor neuropathy, sometimes quite mild and sometimes resembling ALS.  We missed diagnosis of a patient with a late onset motor neuropathy as HEXB is not on the neuropathy panel.  I would suggest that HEXA and HEXB should both be included on this panel. \nSources: Literature",
            "entity_name": "HEXA",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:51:24.146931Z",
            "panel_name": "Hereditary neuropathy NOT PMP22 copy number",
            "panel_id": 846,
            "panel_version": "1.67",
            "user_name": "Evan Reid",
            "item_type": "entity",
            "text": "reviewed gene: HEXB: Rating: ; Mode of pathogenicity: None; Publications: PMID: 31512525, 20798201, 2795083; Phenotypes: ALS, motor neuronopathy; Mode of inheritance: None",
            "entity_name": "HEXB",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:44:59.660108Z",
            "panel_name": "Hereditary neuropathy NOT PMP22 copy number",
            "panel_id": 846,
            "panel_version": "1.67",
            "user_name": "Evan Reid",
            "item_type": "entity",
            "text": "gene: HEXB was added\ngene: HEXB was added to Hereditary neuropathy NOT PMP22 copy number. Sources: Literature\nMode of inheritance for gene: HEXB was set to BIALLELIC, autosomal or pseudoautosomal\nPublications for gene: HEXB were set to PMID: 31512525\nPenetrance for gene: HEXB were set to Complete",
            "entity_name": "HEXB",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:30:49.979906Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.37",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_NHS_review tag was added to gene: SMARCAL1.",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:30:43.634253Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.37",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_NHS_review tag was added to gene: TFE3.",
            "entity_name": "TFE3",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:30:14.411169Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.37",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_rating tag was added to gene: USP9X.\nTag Q4_21_NHS_review tag was added to gene: USP9X.",
            "entity_name": "USP9X",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:30:03.186407Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.37",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: USP9X as Amber List (moderate evidence)",
            "entity_name": "USP9X",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:30:03.182812Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.37",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: New gene added by Tom Cullup (Great Ormond Street Hospital). This gene is associated with a phenotype in OMIM and Gene2Phenotype (probable). There is enough evidence to support a gene-disease association, this gene should be rated Green at the next review.",
            "entity_name": "USP9X",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:30:03.151632Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.37",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: usp9x has been classified as Amber List (Moderate Evidence).",
            "entity_name": "USP9X",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:14:43.885233Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.36",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: USP9X were changed from Intellectual developmental disorder, X-linked 99, syndromic, female-restricted, OMIM:300968; Intellectual developmental disorder, X-linked 99, OMIM:300072 to Intellectual developmental disorder, X-linked 99, syndromic, female-restricted, OMIM:300968",
            "entity_name": "USP9X",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:14:26.764528Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.35",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: USP9X were changed from INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 99, SYNDROMIC, FEMALE-RESTRICTED to Intellectual developmental disorder, X-linked 99, syndromic, female-restricted, OMIM:300968; Intellectual developmental disorder, X-linked 99, OMIM:300072",
            "entity_name": "USP9X",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:12:25.936200Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.34",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_rating tag was added to gene: TFE3.",
            "entity_name": "TFE3",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:12:15.711956Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.34",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: TFE3 as Amber List (moderate evidence)",
            "entity_name": "TFE3",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:12:15.708138Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.34",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: New gene added by Tom Cullup (Great Ormond Street Hospital). This gene is associated with a relevant phenotype in OMIM and Gene2Phenotype (confirmed). There is enough evidence to support a gene-disease association (12/17 patients have skin pigmentation abnormalities), this gene should be Green at the next review.",
            "entity_name": "TFE3",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T13:12:15.672578Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.34",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: tfe3 has been classified as Amber List (Moderate Evidence).",
            "entity_name": "TFE3",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T12:54:17.325015Z",
            "panel_name": "Intellectual disability",
            "panel_id": 285,
            "panel_version": "3.1475",
            "user_name": "Dmitrijs Rots",
            "item_type": "entity",
            "text": "reviewed gene: HMGB1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted",
            "entity_name": "HMGB1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T12:52:42.868116Z",
            "panel_name": "DDG2P",
            "panel_id": 484,
            "panel_version": "2.53",
            "user_name": "Dmitrijs Rots",
            "item_type": "entity",
            "text": "gene: PBX1 was added\ngene: PBX1 was added to DDG2P. Sources: Literature\nMode of inheritance for gene: PBX1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: PBX1 were set to Congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay\nReview for gene: PBX1 was set to GREEN\nAdded comment: Syndromic gene. Most of the individuals present with developmental delay, according to OMIM. \nSources: Literature",
            "entity_name": "PBX1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T12:51:41.080882Z",
            "panel_name": "Hearing loss",
            "panel_id": 126,
            "panel_version": "2.209",
            "user_name": "Dmitrijs Rots",
            "item_type": "entity",
            "text": "gene: PBX1 was added\ngene: PBX1 was added to Hearing loss. Sources: Literature\nMode of inheritance for gene: PBX1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted\nPhenotypes for gene: PBX1 were set to Congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay\nReview for gene: PBX1 was set to GREEN\nAdded comment: Well known disease gene. As OMIM disease name suggests, hearing loss with ear abnormalities is common (reported in at least 5 cases). \nSources: Literature",
            "entity_name": "PBX1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:58:19.115961Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.33",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: TFE3 were changed from Intellectual disability with pigmentary mosaicism and storage disorder-like features to Intellectual developmental disorder, X-linked, syndromic, with pigmentary mosaicism and coarse facies, OMIM:301066",
            "entity_name": "TFE3",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:55:15.100580Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.32",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_rating tag was added to gene: SMARCAL1.",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:55:06.257714Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.32",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: SMARCAL1 as Amber List (moderate evidence)",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:55:06.254341Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.32",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: New gene added by Tom Cullup (Great Ormond Street Hospital). This gene is associated with a relevant phenotype in OMIM and Gene2Phenotype (confirmed). There are >3 unrelated cases and PMID:20301550 reports that ~70% of patients have hyperpigmented macules. Therefore, there is enough evidence to support a gene-disease association. This gene should be rated Green at the next review.",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:55:06.223225Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.32",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: smarcal1 has been classified as Amber List (Moderate Evidence).",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:52:50.482724Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.31",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: SMARCAL1 were set to 11799392",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:45:10.504429Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.30",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: SMARCAL1 were changed from SCHIMKE IMMUNOOSSEOUS DYSPLASIA to Schimke immunoosseous dysplasia, OMIM:242900",
            "entity_name": "SMARCAL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:38:21.606741Z",
            "panel_name": "Growth failure in early childhood",
            "panel_id": 473,
            "panel_version": "1.93",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: PAPPA2 were set to 26902202",
            "entity_name": "PAPPA2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:36:44.806479Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.46",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on publications: Added new publication PMID:33875846",
            "entity_name": "PAPPA2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:36:44.781012Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.46",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: PAPPA2 were set to 26902202",
            "entity_name": "PAPPA2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:29:50.064339Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.45",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: KANSL1 as Green List (high evidence)",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:29:50.061013Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.45",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: New gene added by Andžela Lazdāne (Children's Clinical University Hospital of Latvia). This gene is assiociated with a relevant phenotype in OMIM and Gene2Phenotype (confirmed). There is enough evidence to support a gene-disease association. This gene has been given a Green rating.",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:29:50.041014Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.45",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: kansl1 has been classified as Green List (High Evidence).",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:28:18.812556Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.44",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on publications: PMID: 26306646. Additional 12 cases with de novo variants in KANSL1 causing disease, which further indicates that haploinsufficiency for KANSL1 is sufficient to cause the core phenotype.",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:28:18.787988Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.44",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: KANSL1 were set to 22544363",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:16:41.705028Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.43",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: KANSL1 were set to PMID: 22544363",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:16:26.058589Z",
            "panel_name": "IUGR and IGF abnormalities",
            "panel_id": 131,
            "panel_version": "1.42",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: KANSL1 were changed from Koolen-De Vries syndrome; Facial features; Delayed psychomotor development; Intellectual disability to Koolen-De Vries syndrome, OMIM:610443; Facial features; Delayed psychomotor development; Intellectual disability",
            "entity_name": "KANSL1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:08:50.992347Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.60",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: SYCE1 as Green List (high evidence)",
            "entity_name": "SYCE1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:08:50.989410Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.60",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: This gene is associated with a phenotype in OMIM but not in Gene2Phenotype. There is enough evidence to support a gene-disease association (2 cases + 1 animal model). Therefore, this gene has been promoted from Amber to Green.",
            "entity_name": "SYCE1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:08:50.974955Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.60",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: syce1 has been classified as Green List (High Evidence).",
            "entity_name": "SYCE1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:06:55.600267Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.59",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on publications: PMID: 32917591. Authors made knockin mice with the mouse equivalent variant as Q241X seen in PMID:25062452. Both male and female homozygous mutant mice were infertile and replicated the human phenotype.\r\n\r\nPMID:34718620. An additional case. Patient is compound heterozygous for variants in SYCE1.",
            "entity_name": "SYCE1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T10:06:55.576248Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.59",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: SYCE1 were set to 25062452",
            "entity_name": "SYCE1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T09:55:10.749131Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.58",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: SYCE1 were changed from Premature ovarian failure 12616947 to ?Premature ovarian failure 12, OMIM:616947",
            "entity_name": "SYCE1",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T09:02:14.401009Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.57",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: C14orf39 as Green List (high evidence)",
            "entity_name": "C14orf39",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T09:02:14.397822Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.57",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: Promoted from Amber to Green. There is now enough evidence to support a gene-disease association (2 cases + 1 animal model). This gene has been promoted to Green.",
            "entity_name": "C14orf39",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T09:02:14.382485Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.57",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: c14orf39 has been classified as Green List (High Evidence).",
            "entity_name": "C14orf39",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-30T09:01:25.760496Z",
            "panel_name": "Primary ovarian insufficiency",
            "panel_id": 155,
            "panel_version": "1.56",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: C14orf39 were set to 33508233; 27796301",
            "entity_name": "C14orf39",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:37:09.310848Z",
            "panel_name": "Intellectual disability",
            "panel_id": 285,
            "panel_version": "3.1475",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "reviewed gene: PHF6: Rating: ; Mode of pathogenicity: None; Publications: 24092917, 25099957; Phenotypes: ; Mode of inheritance: X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:36:24.997017Z",
            "panel_name": "Intellectual disability",
            "panel_id": 285,
            "panel_version": "3.1475",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: PHF6 were changed from Borjeson-Forssman-Lehmann syndrome, 301900; BOERJESON-FORSSMAN-LEHMANN SYNDROME (BFLS) to Borjeson-Forssman-Lehmann syndrome, OMIM:301900",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:35:45.961662Z",
            "panel_name": "Intellectual disability",
            "panel_id": 285,
            "panel_version": "3.1474",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: PHF6 were set to ",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:35:03.496511Z",
            "panel_name": "Intellectual disability",
            "panel_id": 285,
            "panel_version": "3.1473",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_MOI tag was added to gene: PHF6.",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:34:29.490540Z",
            "panel_name": "DDG2P",
            "panel_id": 484,
            "panel_version": "2.53",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "reviewed gene: PHF6: Rating: ; Mode of pathogenicity: None; Publications: 24092917, 25099957; Phenotypes: ; Mode of inheritance: X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:33:57.525362Z",
            "panel_name": "Fetal anomalies",
            "panel_id": 478,
            "panel_version": "1.819",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_MOI tag was added to gene: PHF6.",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:32:56.280826Z",
            "panel_name": "Fetal anomalies",
            "panel_id": 478,
            "panel_version": "1.819",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "reviewed gene: PHF6: Rating: ; Mode of pathogenicity: None; Publications: 24092917, 25099957; Phenotypes: ; Mode of inheritance: X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:32:25.301984Z",
            "panel_name": "Fetal anomalies",
            "panel_id": 478,
            "panel_version": "1.819",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: PHF6 were set to ",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:31:59.095416Z",
            "panel_name": "Fetal anomalies",
            "panel_id": 478,
            "panel_version": "1.818",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: PHF6 were changed from BOERJESON-FORSSMAN-LEHMANN SYNDROME to Borjeson-Forssman-Lehmann syndrome, OMIM:301900",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:25:34.593588Z",
            "panel_name": "Severe early-onset obesity",
            "panel_id": 130,
            "panel_version": "2.46",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_MOI tag was added to gene: PHF6.",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:25:24.335484Z",
            "panel_name": "Severe early-onset obesity",
            "panel_id": 130,
            "panel_version": "2.46",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "reviewed gene: PHF6: Rating: ; Mode of pathogenicity: None; Publications: 24092917, 25099957; Phenotypes: ; Mode of inheritance: X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:24:09.617600Z",
            "panel_name": "Severe early-onset obesity",
            "panel_id": 130,
            "panel_version": "2.46",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: PHF6 were set to ",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:21:52.473038Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.29",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Publications for gene: PHF6 were set to 24092917",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:21:35.178841Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.28",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_rating tag was added to gene: PHF6.\nTag Q4_21_NHS_review tag was added to gene: PHF6.",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:21:23.824789Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.28",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: PHF6 as Amber List (moderate evidence)",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:21:23.821868Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.28",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: New gene added by Tom Cullup (Great Ormond Street Hospital). This gene is associated with a relevant phenotype in OMIM and Gene2Phenotype (confirmed). There is enough evidence to support a gene-disease association. This gene should be rated Green at the next review.",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:21:23.800611Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.28",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: phf6 has been classified as Amber List (Moderate Evidence).",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:02:41.830579Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.121",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Publications for gene: RNASEH2B were set to 30223285; 25243380; 29691679; 28762473",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:02:11.746852Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.120",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Classified gene: RNASEH2B as Amber List (moderate evidence)",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:02:11.744224Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.120",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: Sufficient evidence of childhood-onset spasticity associated with variants in this gene. Upgraded from Red to Amber but should be promoted to Green at the next GMS panel update.",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T16:02:11.719688Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.120",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Gene: rnaseh2b has been classified as Amber List (Moderate Evidence).",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:59:27.051384Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.119",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Tag Q4_21_rating tag was added to gene: RNASEH2B.",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:56:58.096205Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.27",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: PHF6 were changed from BORJESON-FORSSMAN-LEHMANN SYNDROME; Fine and whorled Blaschko-linear hypo or hyperpigmentation to Borjeson-Forssman-Lehmann syndrome, OMIM:301900; Fine and whorled Blaschko-linear hypo or hyperpigmentation",
            "entity_name": "PHF6",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:56:49.384584Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.119",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181; spastic paraparesis to Aicardi-Goutieres syndrome 2, OMIM:61018",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:55:34.060288Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.26",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Tag Q4_21_expert_review tag was added to gene: NDUFB11.\nTag Q4_21_NHS_review tag was added to gene: NDUFB11.",
            "entity_name": "NDUFB11",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:55:16.253787Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.26",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Classified gene: NDUFB11 as Amber List (moderate evidence)",
            "entity_name": "NDUFB11",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:55:16.250959Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.26",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Added comment: Comment on list classification: New gene added by Tom Cullup (Great Ormond Street Hospital). This gene is associated with a relevant phenotype in OMIM and Gene2Phenotype (probable). There is currently only 2 published cases of patients with Linear skin defects with multiple congenital anomalies 3. This gene is also associated with Histiocytoid cardiomyopathy and Lactic acidosis and sideroblastic anemia and patients with these diseases do not have signs of skin defects. Therefore, there is currently not enough evidence to support a gene-disease association. This gene has been given an Amber rating.",
            "entity_name": "NDUFB11",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:55:16.227748Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.26",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Gene: ndufb11 has been classified as Amber List (Moderate Evidence).",
            "entity_name": "NDUFB11",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:40:47.162634Z",
            "panel_name": "Pigmentary skin disorders",
            "panel_id": 559,
            "panel_version": "1.25",
            "user_name": "Ivone Leong",
            "item_type": "entity",
            "text": "Phenotypes for gene: NDUFB11 were changed from Linear Skin Defects with Multiple Congenital Anomalies to Linear skin defects with multiple congenital anomalies 3, OMIM:300952",
            "entity_name": "NDUFB11",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:35:52.481446Z",
            "panel_name": "Early onset dystonia",
            "panel_id": 192,
            "panel_version": "1.99",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Dystonia to Aicardi-Goutieres syndrome 2, OMIM:61018",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:35:40.558560Z",
            "panel_name": "White matter disorders and cerebral calcification - narrow panel",
            "panel_id": 476,
            "panel_version": "1.220",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres Syndrome; General Leukodystrophy & Mitochondrial Leukoencephalopathy; Aicardi-Goutieres syndrome 2 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:35:29.108498Z",
            "panel_name": "White matter disorders - adult onset",
            "panel_id": 579,
            "panel_version": "1.36",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:35:19.002275Z",
            "panel_name": "Primary immunodeficiency",
            "panel_id": 398,
            "panel_version": "2.498",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2 610181; Type 1 interferonopathies; Classical AGS, SP; Autoinflammatory Disorders to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:35:01.739829Z",
            "panel_name": "Intracerebral calcification disorders",
            "panel_id": 315,
            "panel_version": "1.34",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2; Aicardi-Goutieres Syndrome to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:34:36.449345Z",
            "panel_name": "Inherited white matter disorders",
            "panel_id": 42,
            "panel_version": "1.150",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres Syndrome; General Leukodystrophy & Mitochondrial Leukoencephalopathy; Aicardi-Goutieres syndrome 2 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T15:33:25.929615Z",
            "panel_name": "Hereditary spastic paraplegia",
            "panel_id": 165,
            "panel_version": "1.276",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181; spastic paraparesis to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:38:10.649474Z",
            "panel_name": "Inborn errors of metabolism",
            "panel_id": 467,
            "panel_version": "2.203",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Intellectual disability; (Disorders of nucleotide metabolism,  Aicardi-Gouti res Syndrome) AGS2; Intracerebral calcification disorders; Inherited white matter disorders to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:38:05.259732Z",
            "panel_name": "Neurodegenerative disorders - adult onset",
            "panel_id": 474,
            "panel_version": "2.257",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Dystonia to Aicardi-Goutieres syndrome 2, OMIM:610181; Dystonia (onset in infancy)",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:37:56.904867Z",
            "panel_name": "Undiagnosed metabolic disorders",
            "panel_id": 302,
            "panel_version": "1.501",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from (Disorders of nucleotide metabolism,  Aicardi-Gouti res Syndrome) AGS2; Inherited white matter disorders; Intellectual disability; Intracerebral calcification disorders to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:37:31.356086Z",
            "panel_name": "Intellectual disability",
            "panel_id": 285,
            "panel_version": "3.1473",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181; AICARDI-GOUTIERES SYNDROME 2 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:37:28.966697Z",
            "panel_name": "Fetal anomalies",
            "panel_id": 478,
            "panel_version": "1.817",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from AICARDI-GOUTIERES SYNDROME 2 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:37:21.294203Z",
            "panel_name": "Genetic epilepsy syndromes",
            "panel_id": 402,
            "panel_version": "2.477",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:37:02.723202Z",
            "panel_name": "Adult onset movement disorder",
            "panel_id": 540,
            "panel_version": "1.161",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181; Dystonia to Aicardi-Goutieres syndrome 2, OMIM:610181; Dystonia (onset in infancy)",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:36:39.490617Z",
            "panel_name": "Adult onset movement disorder",
            "panel_id": 540,
            "panel_version": "1.160",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Mode of inheritance for gene: RNASEH2B was changed from  to BIALLELIC, autosomal or pseudoautosomal",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:36:23.710597Z",
            "panel_name": "Childhood onset dystonia or chorea or related movement disorder",
            "panel_id": 847,
            "panel_version": "1.204",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RNASEH2B were changed from Aicardi-Goutieres syndrome 2, 610181 to Aicardi-Goutieres syndrome 2, OMIM:610181",
            "entity_name": "RNASEH2B",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:24:47.744042Z",
            "panel_name": "Hereditary spastic paraplegia - childhood onset",
            "panel_id": 568,
            "panel_version": "2.118",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RAB3GAP2 were changed from spastic paraplegia to Martsolf syndrome 1, OMIM:212720",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:24:42.183231Z",
            "panel_name": "Hereditary spastic paraplegia",
            "panel_id": 165,
            "panel_version": "1.275",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RAB3GAP2 were changed from spastic paraplegia; Warburg micro syndrome 2, 614225 to Martsolf syndrome 1, OMIM:212720; Warburg micro syndrome 2, OMIM:614225",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:24:35.162454Z",
            "panel_name": "Hereditary spastic paraplegia - adult onset",
            "panel_id": 567,
            "panel_version": "1.88",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RAB3GAP2 were changed from spastic paraplegia; Warburg micro syndrome 2, 614225 to Warburg micro syndrome 2, OMIM:614225",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:20:30.887432Z",
            "panel_name": "Genetic epilepsy syndromes",
            "panel_id": 402,
            "panel_version": "2.476",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Mode of inheritance for gene: RAB3GAP2 was changed from  to BIALLELIC, autosomal or pseudoautosomal",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:08:06.116629Z",
            "panel_name": "Genetic epilepsy syndromes",
            "panel_id": 402,
            "panel_version": "2.475",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RAB3GAP2 were changed from  to Martsolf syndrome 1, OMIM:212720; Warburg micro syndrome 2, OMIM:614225",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T14:03:48.277346Z",
            "panel_name": "Malformations of cortical development",
            "panel_id": 96,
            "panel_version": "2.98",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RAB3GAP2 were changed from Warburg micro syndrome 2, MIM# 614225 to Warburg micro syndrome 2, OMIM:614225",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        },
        {
            "created": "2021-11-29T13:48:52.337202Z",
            "panel_name": "Neurodegenerative disorders - adult onset",
            "panel_id": 474,
            "panel_version": "2.256",
            "user_name": "Arina Puzriakova",
            "item_type": "entity",
            "text": "Phenotypes for gene: RAB3GAP2 were changed from spastic paraplegia to Martsolf syndrome 1, OMIM:212720",
            "entity_name": "RAB3GAP2",
            "entity_type": "gene"
        }
    ]
}