GET /api/v1/panels/945/
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{
    "id": 945,
    "hash_id": null,
    "name": "Thrombocythaemia",
    "disease_group": "Haematological disorders",
    "disease_sub_group": "Haemostasis disorders",
    "status": "public",
    "version": "1.3",
    "version_created": "2022-04-12T11:16:25.488460Z",
    "relevant_disorders": [
        "R406"
    ],
    "stats": {
        "number_of_genes": 5,
        "number_of_strs": 0,
        "number_of_regions": 0
    },
    "types": [
        {
            "name": "GMS Rare Disease",
            "slug": "gms-rare-disease",
            "description": "This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"
        },
        {
            "name": "GMS signed-off",
            "slug": "gms-signed-off",
            "description": "This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."
        }
    ],
    "genes": [
        {
            "gene_data": {
                "alias": [
                    "JTK10"
                ],
                "biotype": "protein_coding",
                "hgnc_id": "HGNC:6192",
                "gene_name": "Janus kinase 2",
                "omim_gene": [
                    "147796"
                ],
                "alias_name": null,
                "gene_symbol": "JAK2",
                "hgnc_symbol": "JAK2",
                "hgnc_release": "2017-11-03",
                "ensembl_genes": {
                    "GRch37": {
                        "82": {
                            "location": "9:4985033-5128183",
                            "ensembl_id": "ENSG00000096968"
                        }
                    },
                    "GRch38": {
                        "90": {
                            "location": "9:4984390-5128183",
                            "ensembl_id": "ENSG00000096968"
                        }
                    }
                },
                "hgnc_date_symbol_changed": "1992-04-16"
            },
            "entity_type": "gene",
            "entity_name": "JAK2",
            "confidence_level": "3",
            "penetrance": null,
            "mode_of_pathogenicity": "",
            "publications": [],
            "evidence": [
                "NHS GMS",
                "Expert Review Green"
            ],
            "phenotypes": [
                "Thrombocythemia 3, 614521"
            ],
            "mode_of_inheritance": "MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
            "tags": [
                "somatic"
            ],
            "transcript": null
        },
        {
            "gene_data": {
                "alias": [
                    "CD110",
                    "TPOR"
                ],
                "biotype": "protein_coding",
                "hgnc_id": "HGNC:7217",
                "gene_name": "MPL proto-oncogene, thrombopoietin receptor",
                "omim_gene": [
                    "159530"
                ],
                "alias_name": null,
                "gene_symbol": "MPL",
                "hgnc_symbol": "MPL",
                "hgnc_release": "2017-11-03",
                "ensembl_genes": {
                    "GRch37": {
                        "82": {
                            "location": "1:43803478-43818443",
                            "ensembl_id": "ENSG00000117400"
                        }
                    },
                    "GRch38": {
                        "90": {
                            "location": "1:43337849-43352772",
                            "ensembl_id": "ENSG00000117400"
                        }
                    }
                },
                "hgnc_date_symbol_changed": "1990-09-10"
            },
            "entity_type": "gene",
            "entity_name": "MPL",
            "confidence_level": "3",
            "penetrance": null,
            "mode_of_pathogenicity": "",
            "publications": [],
            "evidence": [
                "NHS GMS",
                "Expert Review Green"
            ],
            "phenotypes": [
                "Thrombocythemia 2, OMIM:601977"
            ],
            "mode_of_inheritance": "MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
            "tags": [],
            "transcript": null
        },
        {
            "gene_data": {
                "alias": [
                    "TPO",
                    "MPLLG"
                ],
                "biotype": "protein_coding",
                "hgnc_id": "HGNC:11795",
                "gene_name": "thrombopoietin",
                "omim_gene": [
                    "600044"
                ],
                "alias_name": [
                    "prepro-thrombopoietin",
                    "megakaryocyte stimulating factor",
                    "myeloproliferative leukemia virus oncogene ligand",
                    "megakaryocyte growth and development factor",
                    "MPL ligand",
                    "megakaryocyte colony-stimulating factor",
                    "c-mpl ligand",
                    "thrombopoietin nirs variant 1"
                ],
                "gene_symbol": "THPO",
                "hgnc_symbol": "THPO",
                "hgnc_release": "2017-11-03",
                "ensembl_genes": {
                    "GRch37": {
                        "82": {
                            "location": "3:184089723-184095932",
                            "ensembl_id": "ENSG00000090534"
                        }
                    },
                    "GRch38": {
                        "90": {
                            "location": "3:184371935-184378144",
                            "ensembl_id": "ENSG00000090534"
                        }
                    }
                },
                "hgnc_date_symbol_changed": "1994-11-04"
            },
            "entity_type": "gene",
            "entity_name": "THPO",
            "confidence_level": "3",
            "penetrance": null,
            "mode_of_pathogenicity": "",
            "publications": [],
            "evidence": [
                "NHS GMS",
                "Expert Review Green"
            ],
            "phenotypes": [
                "Thrombocythemia 1, 187950"
            ],
            "mode_of_inheritance": "MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown",
            "tags": [],
            "transcript": null
        },
        {
            "gene_data": {
                "alias": [
                    "RO",
                    "SSA",
                    "cC1qR",
                    "CRT",
                    "FLJ26680"
                ],
                "biotype": "protein_coding",
                "hgnc_id": "HGNC:1455",
                "gene_name": "calreticulin",
                "omim_gene": [
                    "109091"
                ],
                "alias_name": [
                    "Sicca syndrome antigen A (autoantigen Ro; calreticulin)",
                    "autoantigen Ro"
                ],
                "gene_symbol": "CALR",
                "hgnc_symbol": "CALR",
                "hgnc_release": "2017-11-03",
                "ensembl_genes": {
                    "GRch37": {
                        "82": {
                            "location": "19:13049392-13055303",
                            "ensembl_id": "ENSG00000179218"
                        }
                    },
                    "GRch38": {
                        "90": {
                            "location": "19:12938578-12944489",
                            "ensembl_id": "ENSG00000179218"
                        }
                    }
                },
                "hgnc_date_symbol_changed": "1990-09-10"
            },
            "entity_type": "gene",
            "entity_name": "CALR",
            "confidence_level": "2",
            "penetrance": null,
            "mode_of_pathogenicity": "",
            "publications": [
                "24325356",
                "24325359",
                "31778606"
            ],
            "evidence": [
                "Expert Review Amber",
                "NHS GMS"
            ],
            "phenotypes": [
                "Thrombocythemia, somatic, 187950",
                "Myelofibrosis, somatic, 254450"
            ],
            "mode_of_inheritance": "Other",
            "tags": [
                "somatic"
            ],
            "transcript": null
        },
        {
            "gene_data": {
                "alias": [
                    "LNK",
                    "IDDM20"
                ],
                "biotype": "protein_coding",
                "hgnc_id": "HGNC:29605",
                "gene_name": "SH2B adaptor protein 3",
                "omim_gene": [
                    "605093"
                ],
                "alias_name": [
                    "lymphocyte adaptor protein"
                ],
                "gene_symbol": "SH2B3",
                "hgnc_symbol": "SH2B3",
                "hgnc_release": "2017-11-03",
                "ensembl_genes": {
                    "GRch37": {
                        "82": {
                            "location": "12:111843752-111889427",
                            "ensembl_id": "ENSG00000111252"
                        }
                    },
                    "GRch38": {
                        "90": {
                            "location": "12:111405948-111451623",
                            "ensembl_id": "ENSG00000111252"
                        }
                    }
                },
                "hgnc_date_symbol_changed": "2006-07-04"
            },
            "entity_type": "gene",
            "entity_name": "SH2B3",
            "confidence_level": "2",
            "penetrance": null,
            "mode_of_pathogenicity": "",
            "publications": [],
            "evidence": [
                "Expert Review Amber",
                "NHS GMS"
            ],
            "phenotypes": [
                "Thrombocythemia, somatic, 187950"
            ],
            "mode_of_inheritance": "Other",
            "tags": [
                "somatic"
            ],
            "transcript": null
        }
    ],
    "strs": [],
    "regions": []
}