Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ABCC9	gene	ABCC9	Literature;North West GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263				27761167;24439875		False	1	0;0;100	3.15	False		ENSG00000069431	ENSG00000069431	HGNC:60													
ANK2	gene	ANK2	Expert list;Expert Review Red;North West GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263				27761167;27818464		False	1	0;25;75	3.15	False		ENSG00000145362	ENSG00000145362	HGNC:493													
CACNA1C	gene	CACNA1C	Emory Genetics Laboratory;Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;London South GLH;Radboud University Medical Center, Nijmegen;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome 3, MONDO:0012742						False	1	0;0;100	3.15	False		ENSG00000151067	ENSG00000151067	HGNC:1390													
CACNA2D1	gene	CACNA2D1	Expert list;Expert Review Red;London South GLH;North West GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263				17224476;20817017;27761167		False	1	0;0;100	3.15	False		ENSG00000153956	ENSG00000153956	HGNC:1399													
CACNB2	gene	CACNB2	Emory Genetics Laboratory;Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;London South GLH;North West GLH;Radboud University Medical Center, Nijmegen;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome 4 (611876)				17224476;27761167		False	1	0;25;75	3.15	False		ENSG00000165995	ENSG00000165995	HGNC:1402													
CAV3	gene	CAV3	Expert list;Expert Review Red;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;50;50	3.15	False		ENSG00000182533	ENSG00000182533	HGNC:1529													
DLG1	gene	DLG1	Expert Review Red;Oxford Medical Genetics Laboratory;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263						False	1	0;0;100	3.15	False		ENSG00000075711	ENSG00000075711	HGNC:2900													
GPD1L	gene	GPD1L	Emory Genetics Laboratory;Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;London South GLH;North West GLH;Radboud University Medical Center, Nijmegen;South West GLH;UKGTN	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome 2, OMIM:611777				27761167;19666841		False	1	0;25;75	3.15	False		ENSG00000152642	ENSG00000152642	HGNC:28956													
HCN4	gene	HCN4	Emory Genetics Laboratory;Expert list;Expert Review Red;London South GLH;North West GLH;Radboud University Medical Center, Nijmegen;South West GLH;UKGTN	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome 8, OMIM:613123				27761167		False	1	25;0;75	3.15	False		ENSG00000138622	ENSG00000138622	HGNC:16882													
KCND3	gene	KCND3	Expert list;Expert Review Red;London South GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome 9, OMIM:616399						False	1	0;0;100	3.15	False		ENSG00000171385	ENSG00000171385	HGNC:6239													
KCNE3	gene	KCNE3	Emory Genetics Laboratory;Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;London South GLH;North West GLH;Radboud University Medical Center, Nijmegen;South West GLH;UKGTN	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	?Brugada syndrome 6, OMIM:613119				19122847;27761167		False	1	0;25;75	3.15	False		ENSG00000175538	ENSG00000175538	HGNC:6243													
KCNE5	gene	KCNE5	Expert Review Red;Oxford Medical Genetics Laboratory;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263				29350269;30289750		False	1	0;0;100	3.15	False		ENSG00000176076	ENSG00000176076	HGNC:6241													
KCNH2	gene	KCNH2	Expert list;Expert Review Red;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263				16043162;19174314;18692916		False	1	17;17;67	3.15	False		ENSG00000055118	ENSG00000055118	HGNC:6251													
KCNJ8	gene	KCNJ8	Expert list;Expert Review Red;London South GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263						False	1	0;0;100	3.15	False		ENSG00000121361	ENSG00000121361	HGNC:6269													
PKP2	gene	PKP2	Literature;London South GLH;North West GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263				27085656;27761167		False	1	0;0;100	3.15	False		ENSG00000057294	ENSG00000057294	HGNC:9024													
RANGRF	gene	RANGRF	Expert list;Expert Review Red;London South GLH;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263						False	1	0;33;67	3.15	False		ENSG00000108961	ENSG00000108961	HGNC:17679													
SCN10A	gene	SCN10A	Expert Review Red;London South GLH;North West GLH;Oxford Medical Genetics Laboratory;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263				24998131;27761167		False	1	25;0;75	3.15	False		ENSG00000185313	ENSG00000185313	HGNC:10582													
SCN1B	gene	SCN1B	Emory Genetics Laboratory;Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;London South GLH;North West GLH;Radboud University Medical Center, Nijmegen;South West GLH;UKGTN	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Cardiac conduction defect, nonspecific, OMIM:612838;Brugada syndrome 5, OMIM:612838;Atrial fibrillation, familial, 13, OMIM:615377				25253298;27761167		False	1	25;0;75	3.15	False		ENSG00000105711	ENSG00000105711	HGNC:10586													
SCN2B	gene	SCN2B	Expert Review Red;Oxford Medical Genetics Laboratory;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263						False	1	0;0;100	3.15	False		ENSG00000149575	ENSG00000149575	HGNC:10589													
SCN3B	gene	SCN3B	Emory Genetics Laboratory;Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;London South GLH;North West GLH;Radboud University Medical Center, Nijmegen;South West GLH;UKGTN	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome 7, OMIM:613120				23257389;27761167		False	1	25;0;75	3.15	False		ENSG00000166257	ENSG00000166257	HGNC:20665													
SLMAP	gene	SLMAP	Expert list;Expert Review Red;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	Unknown	Brugada syndrome, MONDO:0015263						False	1	0;0;100	3.15	False		ENSG00000163681	ENSG00000163681	HGNC:16643													
TRPM4	gene	TRPM4	Expert Review Red;North West GLH;Oxford Medical Genetics Laboratory;South West GLH	Brugada syndrome and cardiac sodium channel disease		Cardiology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Brugada syndrome, MONDO:0015263				23382873;27761167		False	1	25;0;75	3.15	False		ENSG00000130529	ENSG00000130529	HGNC:17993