Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
AKR1C2	gene	AKR1C2	Expert list;Expert Review Red;Radboud University Medical Center, Nijmegen	Severe early-onset obesity		Endocrinology		Obesity, hyperphagia, and developmental delay						False	1	0;0;100	5.21	False		ENSG00000151632	ENSG00000151632	HGNC:385													
MAGEL2	gene	MAGEL2	Emory Genetics Laboratory;Expert list	Severe early-onset obesity		Endocrinology		Congenital Obesity						False	1	0;0;100	5.21	False		ENSG00000254585	ENSG00000254585	HGNC:6814													
MC3R	gene	MC3R	Expert Review Red;Literature	Severe early-onset obesity		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{Obesity, severe, susceptibility to, BMIQ9}, OMIM:602025				31090190		False	1	50;0;50	5.21	False		ENSG00000124089	ENSG00000124089	HGNC:6931													
MRAP2	gene	MRAP2	Expert list;Expert Review;Expert Review Red	Severe early-onset obesity		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{?Obesity, susceptibility to, BMIQ18}, OMIM:615457				23869016;26795956;27474872;31700171		False	1	33;33;33	5.21	False		ENSG00000135324	ENSG00000135324	HGNC:21232													
NR0B2	gene	NR0B2	Emory Genetics Laboratory;Expert list;Expert Review Red;Radboud University Medical Center, Nijmegen	Severe early-onset obesity		Endocrinology		Obesity, mild, early-onset, 601665;Congenital Obesity						False	1	0;0;100	5.21	False		ENSG00000131910	ENSG00000131910	HGNC:7961													
PPARG	gene	PPARG	Expert list;Expert Review Red;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen	Severe early-onset obesity		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Obesity, severe, 601665; [Obesity, resistance to]; Insulin resistance, severe, digenic, 604367; Lipodystrophy, familial partial, type 3, 604367; Carotid intimal medial thickness 1, 609338; {Diabetes, type 2}, 125853						False	1	0;0;100	5.21	False		ENSG00000132170	ENSG00000132170	HGNC:9236													
TRIM32	gene	TRIM32	Emory Genetics Laboratory;Expert list;Expert Review Red	Severe early-onset obesity		Endocrinology	BIALLELIC, autosomal or pseudoautosomal	?Bardet-Biedl syndrome 11;615988						False	1	50;0;50	5.21	False		ENSG00000119401	ENSG00000119401	HGNC:16380													
WDPCP	gene	WDPCP	Emory Genetics Laboratory;Expert list;Expert Review Red	Severe early-onset obesity		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Congenital Obesity				26518167		False	1	50;0;50	5.21	False		ENSG00000143951	ENSG00000143951	HGNC:28027