Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
CARD14	gene	CARD14	Expert Review Green;Radboud University Medical Center, Nijmegen	Generalised pustular psoriasis	Autoimmune skin disorders	Dermatological disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Psoriasis 2, OMIM:602723;Pityriasis rubra pilaris, OMIM:173200				26203641;23648549;22521418;22703878;23067081;29704870;29689250		False	3	0;0;100	1.13	False	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000141527	ENSG00000141527	HGNC:16446													
IL36RN	gene	IL36RN	Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen	Generalised pustular psoriasis	Autoimmune skin disorders	Dermatological disorders	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Psoriasis 14, pustular, OMIM:614204				21839423;25458002;27388993		False	3	100;0;0	1.13	False		ENSG00000136695	ENSG00000136695	HGNC:15561