Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
APC	gene	APC	Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Adenomatous polyposis coli  (Thyroid papillary carcinoma in patients with APC) 175100				https://doi.org/10.1016/j.mpdhp.2016.02.005;28490611;26697262		False	3	100;0;0	1.8	False		ENSG00000134982	ENSG00000134982	HGNC:583													
DICER1	gene	DICER1	Expert Review Green;Radboud University Medical Center, Nijmegen	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors, OMIM:138800				9345104;21266384;28323992		False	3	100;0;0	1.8	False		ENSG00000100697	ENSG00000100697	HGNC:17098													
PRKAR1A	gene	PRKAR1A	Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Carney complex, type 1 160980				9215269;27943004		False	3	100;0;0	1.8	False		ENSG00000108946	ENSG00000108946	HGNC:9388													
PTEN	gene	PTEN	Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Cowden syndrome 1 158350; Lhermitte-Duclos syndrome 158350				9790504;https://doi.org/10.1016/j.mpdhp.2016.02.005;10594284;22252256		False	3	100;0;0	1.8	False		ENSG00000171862	ENSG00000171862	HGNC:9588													
WRN	gene	WRN	Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Literature;Radboud University Medical Center, Nijmegen;UKGTN	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	BIALLELIC, autosomal or pseudoautosomal	Werner syndrome 277700				8722214;23573208;8602509		False	3	100;0;0	1.8	False		ENSG00000165392	ENSG00000165392	HGNC:12791													
FOXE1	gene	FOXE1	Expert Review Amber;Radboud University Medical Center, Nijmegen	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{Thyroid cancer, nonmedullary, 4} 616534				25381600		False	2	0;0;100	1.8	False		ENSG00000178919	ENSG00000178919	HGNC:3806													
MSH2	gene	MSH2	Expert Review Amber;Literature	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Familial Non-medullary Thyroid Cancer				26530882;22714864		False	2	100;0;0	1.8	False		ENSG00000095002	ENSG00000095002	HGNC:7325													
SLC5A5	gene	SLC5A5	Expert Review Amber;Illumina TruGenome Clinical Sequencing Services;Literature;Radboud University Medical Center, Nijmegen	Inherited non-medullary thyroid cancer	Breast and endocrine	Tumour syndromes	BIALLELIC, autosomal or pseudoautosomal	"Follicular thyroid adenoma;Thyroid dyshormonogenesis 1	274400"				9171822;9661633;10487692;9709973;26960757		False	2	0;0;100	1.8	False		ENSG00000105641	ENSG00000105641	HGNC:11040