Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
CAST	gene	CAST	Expert Review Green;Research	Peeling skin syndrome	Skin fragility disorders	Dermatological disorders	BIALLELIC, autosomal or pseudoautosomal	Peeling skin with leukonychia, acral punctate keratoses, cheilitis, and knuckle pads, 616295; OMIM:#616295; Peeling skin HP:0040189; Leukonychia HP:0001820; Punctate palmoplantar hyperkeratosis HP:0007530; Cheilitis HP:0100825; Knuckle pads.				PMID: 25683118		False	3	100;0;0	1.5	False		ENSG00000153113	ENSG00000153113	HGNC:1515													
CDSN	gene	CDSN	Expert Review Green;Literature	Peeling skin syndrome	Skin fragility disorders	Dermatological disorders	BIALLELIC, autosomal or pseudoautosomal	Peeling skin syndrome 1, OMIM:270300;Peeling skin HP:0040189;Pruritus HP:0000989;Allergy HP:0012393;Increased IgE level HP:0003212;Generalised erythroderma HP:0001019;erythema HP:0010783;Hyperkeratosis HP:0000962.				PMID: 20691404; 22146835; 21191406; 23957618		False	3	100;0;0	1.5	False		ENSG00000204539	ENSG00000204539	HGNC:1802													
CSTA	gene	CSTA	Expert Review Green;Research	Peeling skin syndrome	Skin fragility disorders	Dermatological disorders	BIALLELIC, autosomal or pseudoautosomal	Peeling skin syndrome 4, 607936; OMIM:607936;Peeling skin HP:0040189;Ichthyosis HP:0008064;skin erosions HP:0200041;erythema HP:0010783;palmoplantar hyperkeratosis HP:0007530;Hyperhidrosis HP:0000975;Lichenification HP:0100725;Hyperkeratosis HP:0000962;Erythroderma HP:0001019				PMID: 21944047;23534700;25400170;26684698		False	3	100;0;0	1.5	False		ENSG00000121552	ENSG00000121552	HGNC:2481													
SERPINB8	gene	SERPINB8	Expert Review Green;Research	Peeling skin syndrome	Skin fragility disorders	Dermatological disorders	BIALLELIC, autosomal or pseudoautosomal	Peeling skin syndrome 5, 617115; Peeling skin HP:0040189;Ichthyosis HP:0008064;skin erosions HP:0200041;erythema HP:0010783;palmoplantar hyperkeratosis HP:0007530				27476651		False	3	100;0;0	1.5	False		ENSG00000166401	ENSG00000166401	HGNC:8952													
TGM5	gene	TGM5	Eligibility statement prior genetic testing;Expert Review Green;Other	Peeling skin syndrome	Skin fragility disorders	Dermatological disorders	BIALLELIC, autosomal or pseudoautosomal	Peeling skin syndrome 2, 609796; acral peeling skin						False	3	100;0;0	1.5	False		ENSG00000104055	ENSG00000104055	HGNC:11781