Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
EZH2	gene	EZH2	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Weaver syndrome, 277590						False	2	0;0;0	1.30	False		ENSG00000106462	ENSG00000106462	HGNC:3527													
FANCB	gene	FANCB	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Fanconi anemia, complementation group B, 300514						False	2	0;0;0	1.30	False		ENSG00000181544	ENSG00000181544	HGNC:3583													
FANCM	gene	FANCM	Expert list;Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	BIALLELIC, autosomal or pseudoautosomal	Fanconi Anemia				19686080;28376765		False	2	50;50;0	1.30	False		ENSG00000187790	ENSG00000187790	HGNC:23168													
GPC3	gene	GPC3	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Wilms tumor, somatic, 194070;Simpson-Golabi-Behmel syndrome, type 1, 312870						False	2	0;0;0	1.30	False		ENSG00000147257	ENSG00000147257	HGNC:4451													
NOP10	gene	NOP10	Expert list;Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	BIALLELIC, autosomal or pseudoautosomal	Dyskeratosis congenita, autosomal recessive 1, 224230				22965356		False	2	50;0;50	1.30	False		ENSG00000182117	ENSG00000182117	HGNC:14378													
NSD1	gene	NSD1	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sotos syndrome 1, 117550						False	2	0;0;0	1.30	False		ENSG00000165671	ENSG00000165671	HGNC:14234													
PDGFRA	gene	PDGFRA	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Gastrointestinal stromal tumor/GIST-plus syndrome, somatic or familial, OMIM:175510;Familial Gastrointestinal stromal tumour;Familial GIST						False	2	0;0;0	1.30	False		ENSG00000134853	ENSG00000134853	HGNC:8803													
RAD51C	gene	RAD51C	Expert list;Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	BIALLELIC, autosomal or pseudoautosomal	Fanconi Anemia				19686080		False	2	100;0;0	1.30	False		ENSG00000108384	ENSG00000108384	HGNC:9820													
REST	gene	REST	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{Wilms tumor 6, susceptibility to} 616806						False	2	0;0;0	1.30	False		ENSG00000084093	ENSG00000084093	HGNC:9966													
SLX4	gene	SLX4	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	BIALLELIC, autosomal or pseudoautosomal	Fanconi anemia, complementation group P, 613951						False	2	0;0;0	1.30	False		ENSG00000188827	ENSG00000188827	HGNC:23845													
SQSTM1	gene	SQSTM1	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Paget disease of bone 3 167250;Osteosarcoma						False	2	0;0;0	1.30	False		ENSG00000161011	ENSG00000161011	HGNC:11280													
TRIM37	gene	TRIM37	Expert Review Amber	Childhood solid tumours cancer susceptibility	Pertinent cancer susceptibility gene panel	Cancer Programme	BIALLELIC, autosomal or pseudoautosomal	Mulibrey nanism 253250						False	2	0;0;0	1.30	False		ENSG00000108395	ENSG00000108395	HGNC:7523