Entity Name Entity type Gene Symbol Sources(; separated) Level4 Level3 Level2 Model_Of_Inheritance Phenotypes Omim Orphanet HPO Publications Description Flagged GEL_Status UserRatings_Green_amber_red version ready Mode of pathogenicity EnsemblId(GRch37) EnsemblId(GRch38) HGNC Position Chromosome Position GRCh37 Start Position GRCh37 End Position GRCh38 Start Position GRCh38 End STR Repeated Sequence STR Normal Repeats STR Pathogenic Repeats Region Haploinsufficiency Score Region Triplosensitivity Score Region Required Overlap Percentage Region Variant Type Region Verbose Name ABCC8 gene ABCC8 Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BOTH monoallelic and biallelic, autosomal or pseudoautosomal Hyperinsulinemic hypoglycemia, familial, 1, 256450; Hypoglycemia of infancy, leucine-sensitive, 240800; Diabetes mellitus, transient neonatal 2, 610374; Diabetes mellitus, noninsulin-dependent, 125853; Diabetes mellitus, permanent neonatal, 6;Permanent Neonatal Diabetes Mellitus;Transient Neonatal Diabetes, Dominant;Permanent neonatal diabetes mellitus; transient neonatal diabetes (Dominant);DIABETES MELLITUS, NONINSULIN-DEPENDENT False 3 100;0;0 1.69 False ENSG00000006071 ENSG00000006071 HGNC:59 AGPAT2 gene AGPAT2 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal lipodystrophy 11967537;12765973 False 3 100;0;0 1.69 True ENSG00000169692 ENSG00000169692 HGNC:325 ALMS1 gene ALMS1 Eligibility statement prior genetic testing;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Alstrom syndrome False 3 100;0;0 1.69 False ENSG00000116127 ENSG00000116127 HGNC:428 BSCL2 gene BSCL2 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Lipodystrophy, congenital generalized, type 2, OMIM:269700 11479539 False 3 100;0;0 1.69 True ENSG00000168000 ENSG00000168000 HGNC:15832 CISD2 gene CISD2 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal 604928;Wolfram syndrome 2 17846994;25056293 False 3 100;0;0 1.69 False ENSG00000145354 ENSG00000145354 HGNC:24212 EIF2AK3 gene EIF2AK3 Expert Review Green;Illumina TruGenome Clinical Sequencing Services;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Multiple Epiphyseal Dysplasia with Early-Onset Diabetes Mellitus;Wolcott-Rallison syndrome False 3 100;0;0 1.69 False ENSG00000172071 ENSG00000172071 HGNC:3255 FOXP3 gene FOXP3 Expert Review Green;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders X-LINKED: hemizygous mutation in males, biallelic mutations in females Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked, 304790; {Diabetes mellitus, type I, susceptibility to}, 222100;IPEX syndrome False 3 100;0;0 1.69 False ENSG00000049768 ENSG00000049768 HGNC:6106 GATA4 gene GATA4 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Neonatal diabetes, Pancreatic agenesis and/or congenital heart defects 24696446 False 3 100;0;0 1.69 False ENSG00000136574 ENSG00000136574 HGNC:4173 GATA6 gene GATA6 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Pancreatic agenesis and congenital heart defects ;PANCREATIC AGENESIS AND CONGENITAL HEART DEFECTS Lango Allen et al 2011 Nat Genet 44, 20-22 De Franco et al 2013 Diabetes 62, 993-997;27098067;26210631;25706805;25708516;25356219;24433315;24310933;23639568;23635550;22962692;22806356;22158542 False 3 100;0;0 1.69 False ENSG00000141448 ENSG00000141448 HGNC:4174 GCK gene GCK Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal MODY, type II, 125851; Diabetes mellitus, noninsulin-dependent, late onset, 125853; Diabetes mellitus, gestational, 125851; Hyperinsulinemic hypoglycemia, familial, 3, 602485; Diabetes mellitus, permanent neonatal, 606176;Maturity Onset Diabetes of the Young;Permanent Neonatal Diabetes Mellitus;Transient Neonatal Diabetes, Recessive;Maturity-onset diabetes of the young (MODY);Maturity-Onset Diabetes Of The Young;Permanent neonatal diabetes ;MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 2; MODY2 False 3 100;0;0 1.69 False ENSG00000106633 ENSG00000106633 HGNC:4195 GLIS3 gene GLIS3 Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Diabetes mellitus, neonatal, with congenital hypothyroidism, 610199 -3;Diabetes Mellitus, Neonatal, with Congenital Hypothyroidism;Diabetes Mellitus, Neonatal, With Congenital Hypothyroidism;Neonatal Diabetes mellitus with congenital hypothyroidism False 3 100;0;0 1.69 False ENSG00000107249 ENSG00000107249 HGNC:28510 HAMP gene HAMP Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Hemochromatosis, type 2B 613313 False 3 100;0;0 1.69 False ENSG00000105697 ENSG00000105697 HGNC:15598 HFE gene HFE Expert Review Green;Radboud University Medical Center, Nijmegen Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Hemochromatosis, 235200; {Microvascular complications of diabetes 7}, 612635; {Porphyria variegata, susceptibility to}, 176200; {Porphyria cutanea tarda, susceptibility to}, 176100; {Alzheimer disease, susceptibility to}, 104300 False 3 100;0;0 1.69 False ENSG00000010704 ENSG00000010704 HGNC:4886 HFE2 gene HFE2 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Hemochromatosis, type 2A, 602390 False 3 100;0;0 1.69 False ENSG00000168509 ENSG00000168509 HGNC:4887 HNF1A gene HNF1A Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Diabetes mellitus, insulin-dependent, 20, OMIM:612520;{Diabetes mellitus, noninsulin-dependent, 2}, OMIM:125853;MODY, type III, OMIM:600496 False 3 100;0;0 1.69 False ENSG00000135100 ENSG00000135100 HGNC:11621 HNF1B gene HNF1B Eligibility statement prior genetic testing;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Renal cysts and diabetes syndrome, 137920; Diabetes mellitus, noninsulin-dependent, 125853; {Renal cell carcinoma}, 144700;Renal Cysts and Diabetes Syndrome;Maturity-Onset Diabetes Of The Young;Transient neonatal diabetes ;RENAL CYSTS AND DIABETES SYNDROME; RCAD ;renal malformation False 3 100;0;0 1.69 False ENSG00000108753 ENSG00000275410 HGNC:11630 HNF4A gene HNF4A Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted MODY, type I, 125850;{Diabetes mellitus, noninsulin-dependent}, 125853;Maturity Onset Diabetes of the Young;Maturity-onset diabetes of the young (MODY);Maturity-Onset Diabetes Of The Young;MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 1;MODY1;#616026 False 3 100;0;0 1.69 False ENSG00000101076 ENSG00000101076 HGNC:5024 IER3IP1 gene IER3IP1 Expert Review Green;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Microcephaly, epilepsy, and diabetes syndrome, 614231;Microcephaly, epilepsy and diabetes syndrome 21835305, 22991235, 24138066 False 3 0;0;100 1.69 True ENSG00000134049 ENSG00000134049 HGNC:18550 INS gene INS Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BOTH monoallelic and biallelic, autosomal or pseudoautosomal Hyperproinsulinemia, familial, with or without diabetes; Maturity-onset diabetes of the young, type 10, 613370; Diabetes mellitus, permanent neonatal, 606176; Diabetes mellitus, type 1, 125852; Diabetes mellitus, insulin-dependent, 2, 125852;Maturity Onset Diabetes of the Young;Transient Neonatal Diabetes, Dominant/Recessive;Permanent Neonatal diabetes mellitus ;MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 10; MODY10 False 3 100;0;0 1.69 False ENSG00000254647 ENSG00000254647 HGNC:6081 INSR gene INSR Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Diabetes mellitus, insulin-resistant, with acanthosis nigricans;OMIM 610549;Leprechaunism, 246200;Rabson-Mendenhall syndrome, 262190;Diabetes mellitus, insulin-resistant, with acanthosis nigricans, 610549;Hyperinsulinemic hypoglycemia, familial, 5, 609968;Diabetes Mellitus, Insulin Resistant, with Acanthosis Nigricans;Pineal Hyperplasia,Insulin- Resistant Diabetes Mellitus, and Somatic Abnormalities;Diabetes Mellitus, Insulin-Resistant, With Acanthosis Nigricans;Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities;DIABETES MELLITUS, INSULIN-RESISTANT, WITH ACANTHOSIS NIGRICANS 8288049 False 3 100;0;0 1.69 False ENSG00000171105 ENSG00000171105 HGNC:6091 KCNJ11 gene KCNJ11 Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Hyperinsulinemic hypoglycemia, familial, 2, 601820; Diabetes, permanent neonatal, 606176; Diabetes mellitus, permanent neonatal, with neurologic features, 606176;{Diabetes mellitus, type 2, susceptibility to}, 125853; Diabetes mellitus, transient neonatal, 3, 610582; {Diabetes mellitus, type 2, susceptibility to}, 125853; Diabetes mellitus, trans;Maturity Onset Diabetes of the Young;Transient Neonatal Diabetes, Dominant;Diabetes Mellitus, Permanent Neonatal; Diabetes Mellitus, Transient Neonatal, 3; Transient Neonatal diabetes mellitus (Dominant); Maturity Onset Diabetes of the Young (Dominant);Diabetes Mellitus, Permanent Neonatal diabetes mellitus (Dominant and recessive); Transient Neonatal, 3 False 3 100;0;0 1.69 False Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments ENSG00000187486 ENSG00000187486 HGNC:6257 LMNA gene LMNA Expert Review Green;Illumina TruGenome Clinical Sequencing Services;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Lipoatrophy with Diabetes, Hepatic Steatosis, Hypertrophic Cardiomyopathy, and Leukomelanodermic Papules;LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 2; FPLD2 26775134;24002959 False 3 100;0;0 1.69 False ENSG00000160789 ENSG00000160789 HGNC:6636 LRBA gene LRBA Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Immunodeficiency, common variable, 8, with autoimmunity 25468195; 26206937; 26745254; 27057999; 25479458 False 3 100;0;0 1.69 True ENSG00000198589 ENSG00000198589 HGNC:1742 MNX1 gene MNX1 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Flanagan et al 2014 Cell Metab 19:146-154;23562494;24411943;26534984 False 3 100;0;0 1.69 False ENSG00000130675 ENSG00000130675 HGNC:4979 MT-TL1 gene MT-TL1 Eligibility statement prior genetic testing;Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MITOCHONDRIAL MELAS syndrome;Diabetes-Deafness Syndrome, Maternally Transmitted;DIABETES AND DEAFNESS, MATERNALLY INHERITED;MIDD False 3 100;0;0 1.69 False ENSG00000209082 ENSG00000209082 HGNC:7490 NEUROD1 gene NEUROD1 Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BOTH monoallelic and biallelic, autosomal or pseudoautosomal {Diabetes mellitus, noninsulin-dependent}, 125853; Maturity-onset diabetes of the young 6, 606394;Maturity Onset Diabetes of the Young;Maturity-Onset Diabetes Of The Young;Permanent neonatal diabetes and cerebellar agenesis ;MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 6; MODY6 26773576;10545951;20573748;26669242 False 3 100;0;0 1.69 False ENSG00000162992 ENSG00000162992 HGNC:7762 NEUROG3 gene NEUROG3 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Permanent neonatal diabetes and enteric anendocrinosis Rubio-Cabezas et al 2011 Diabetes 60:1349-1353;26288179;25650326 False 3 100;0;0 1.69 False ENSG00000122859 ENSG00000122859 HGNC:13806 NKX2-2 gene NKX2-2 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal 24411943 False 3 100;0;0 1.69 False ENSG00000125820 ENSG00000125820 HGNC:7835 PDX1 gene PDX1 Emory Genetics Laboratory;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal MODY type IV;Maturity-onset diabetes of the young (MODY);Maturity-Onset Diabetes Of The Young;Permanent neonatal diabetes ;MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 4; MODY4 False 3 0;0;0 1.69 False ENSG00000139515 ENSG00000139515 HGNC:6107 PIK3R1 gene PIK3R1 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Short stature, hyperextensibility of joints and/or inguinal hernia, ocular depression, Rieger anomaly, and teething delay (SHORT) syndrome 23810378 False 3 100;0;0 1.69 True ENSG00000145675 ENSG00000145675 HGNC:8979 POLD1 gene POLD1 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome, OMIM:615381 23770608 False 3 100;0;0 1.69 True Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments ENSG00000062822 ENSG00000062822 HGNC:9175 PPARG gene PPARG Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Obesity, severe, 601665; [Obesity, resistance to]; Insulin resistance, severe, digenic, 604367; Lipodystrophy, familial partial, type 3, 604367; Carotid intimal medial thickness 1, 609338; {Diabetes, type 2}, 125853;Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigricans and Hypertension;LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 3; FPLD3 False 3 100;0;0 1.69 False ENSG00000132170 ENSG00000132170 HGNC:9236 PTF1A gene PTF1A Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Diabetes mellitus, permanent neonatal, with cerebellar agenesis, 609069;Permanent neonatal diabetes mellitus (PNDM);Permanent neonatal diabetes with cerebellar agenesis False 3 100;0;0 1.69 False ENSG00000168267 ENSG00000168267 HGNC:23734 RFX6 gene RFX6 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Neonatal diabetes, intestinal atresia and hepatobiliary abnormalities;Mitchell-Riley syndrome Spiegal et al 2011 AM J Med Genet 155:2821-2825;Smith et al 2010 Nature 463:775-780;27185633;27167055;26770845;26761945;26559129;26264437;25048417 False 3 100;0;0 1.69 False ENSG00000185002 ENSG00000185002 HGNC:21478 SLC19A2 gene SLC19A2 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Thiamine-responsive megaloblastic anemia syndrome, OMIM:249270;diabetes mellitus, MONDO:0005015 Shaw-Smith et al 2012 Pediatr Diabetes 13:314-321;26839896;26549656 False 3 100;0;0 1.69 False ENSG00000117479 ENSG00000117479 HGNC:10938 SLC29A3 gene SLC29A3 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Histiocytosis-lymphadenopathy plus syndrome, OMIM:602782;Pigmented hypertrichotic dermatosis with insulin-dependent diabetes (PHID) syndrome 19336477 False 3 100;0;0 1.69 True ENSG00000198246 ENSG00000198246 HGNC:23096 SLC2A2 gene SLC2A2 Expert Review Green;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal {Diabetes mellitus, noninsulin-dependent}; Fanconi-Bickel syndrome, 227810;Fanconi-Bickel syndrome 23456528;22660720;22831748 False 3 100;0;0 1.69 False ENSG00000163581 ENSG00000163581 HGNC:11006 SLC40A1 gene SLC40A1 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Hemochromatosis, type 4 606069 False 3 100;0;0 1.69 False ENSG00000138449 ENSG00000138449 HGNC:10909 STAT3 gene STAT3 Expert Review Green;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Neonatal diabetes and additional multi-organ autoimmunity Flanagan et al 2014 Nature Genetics (In press);27167055 False 3 100;0;0 1.69 False Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments ENSG00000168610 ENSG00000168610 HGNC:11364 TFR2 gene TFR2 Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Hemochromatosis, type 3 604250 False 3 100;0;0 1.69 False ENSG00000106327 ENSG00000106327 HGNC:11762 TRMT10A gene TRMT10A Expert Review;Expert Review Green Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal young onset diabetes, short stature and microcephaly with intellectual disability; failure to thrive and microcephaly, ketoacidosis at onset of diabetes and islet cell autoantibodies 24204302; 26297882 False 3 100;0;0 1.69 True ENSG00000145331 ENSG00000145331 HGNC:28403 WFS1 gene WFS1 Eligibility statement prior genetic testing;Expert Review Green;Radboud University Medical Center, Nijmegen Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BOTH monoallelic and biallelic, autosomal or pseudoautosomal Wolfram syndrome, OMIM:222300;Deafness, autosomal dominant 6/14/38, OMIM:600965;Wolfram-like syndrome, autosomal dominant, OMIM:614296;{Diabetes mellitus, noninsulin-dependent, association with}, OMIM:125853;?Cataract 41, OMIM:116400;diabetes insipidus or optic atrophy 27217304;27185633;33693650 False 3 100;0;0 1.69 False ENSG00000109501 ENSG00000109501 HGNC:12762 ZFP57 gene ZFP57 Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders BIALLELIC, autosomal or pseudoautosomal Diabetes mellitus, transient neonatal, 1, 601410;Transient Neonatal Diabetes, Recessive;Transient Neonatal Diabetes False 3 100;0;0 1.69 False ENSG00000204644 ENSG00000204644 HGNC:18791 ISCA-37432-Loss region Expert Review Green;ClinGen Diabetes with additional phenotypes suggestive of a monogenic aetiology Disorders of unusual phenotypes Endocrine disorders MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown RCAD syndrome;utero-vaginal atresia;Schizophrenia;614527;delayed development, intellectual disability;Renal cysts and diabetes syndrome;Autism Spectrum Disorder;Mayer-Rokitansky-Kster-Hauser (MRKH) syndrome in females;Chromosome 17q12 deletion syndrome;global developmental delay False 3 0;0;0 1.69 False 17 36458167 37854616 3 60 cnv_loss 17q12 recurrent (RCAD syndrome) region (includes HNF1B) Loss