Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
AIP	gene	AIP	Eligibility statement prior genetic testing;Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	pituitary tumours;Familial Isolated Pituitary Adenomas; Pituitary adenoma, growth hormone-secreting, 102200; Pituitary adenoma, prolactin-secreting, 600634; Pituitary adenoma, ACTH-secreting, 219090;Endocrine Cancer						False	3	100;0;0	1.15	True		ENSG00000110711	ENSG00000110711	HGNC:358													
CDC73	gene	CDC73	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer						False	3	100;0;0	1.15	True		ENSG00000134371	ENSG00000134371	HGNC:16783													
CDKN1B	gene	CDKN1B	Emory Genetics Laboratory;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Multiple endocrine neoplasia, type IV, OMIM:610755						False	3	100;0;0	1.15	True		ENSG00000111276	ENSG00000111276	HGNC:1785													
MAX	gene	MAX	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{Pheochromocytoma, susceptibility to}, OMIM:171300				PubMed: 21685915		False	3	100;0;0	1.15	True		ENSG00000125952	ENSG00000125952	HGNC:6913													
MEN1	gene	MEN1	Eligibility statement prior genetic testing;Emory Genetics Laboratory;Expert;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Multiple Endocrine Neoplasia Type 1: MEN1 Gene Deletion/Duplication;Multiple Endocrine Neoplasia;Multiple endocrine neoplasia 1, 131100;Carcinoid tumor of lung;Parathyroid adenoma, somatic;Lipoma, somatic;Angiofibroma, somatic;Adrenal adenoma, somatic;MEN1-like spectrum;pituitary tumours;Endocrine Cancer						False	3	100;0;0	1.15	True		ENSG00000133895	ENSG00000133895	HGNC:7010													
PRKAR1A	gene	PRKAR1A	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer						False	3	100;0;0	1.15	True		ENSG00000108946	ENSG00000108946	HGNC:9388													
RET	gene	RET	Eligibility statement prior genetic testing;Emory Genetics Laboratory;Expert list;Expert Review Green;Illumina TruGenome Clinical Sequencing Services;Radboud University Medical Center, Nijmegen;UKGTN	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Multiple endocrine neoplasia IIA, 171400;Multiple Endocrine Neoplasia;Multiple Endocrine Neoplasia Type 2: RET Gene Deletion/Duplication;MEN2-like spectrum; Endocrine Cancer						False	3	100;0;0	1.15	True		ENSG00000165731	ENSG00000165731	HGNC:9967													
SDHAF2	gene	SDHAF2	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Endocrine Cancer;familial paraganglioma						False	3	100;0;0	1.15	True	Other - please provide details in the comments	ENSG00000167985	ENSG00000167985	HGNC:26034													
SDHB	gene	SDHB	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paragangliomas 4, OMIM:115310;Pheochromocytoma, OMIM:171300;Paraganglioma and gastric stromal sarcoma, OMIM:606864						False	3	100;0;0	1.15	True		ENSG00000117118	ENSG00000117118	HGNC:10681													
SDHC	gene	SDHC	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer						False	3	100;0;0	1.15	True		ENSG00000143252	ENSG00000143252	HGNC:10682													
SDHD	gene	SDHD	Emory Genetics Laboratory;Expert Review Green;Radboud University Medical Center, Nijmegen	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed)	Endocrine Cancer; Paragangliomas 1, with or without deafness, 168000; Pheochromocytoma, 171300; Carcinoid tumors, intestinal, 114900; Merkel cell carcinoma, somatic; Paraganglioma and gastric stromal sarcoma, 606864; Cowden syndrome 3, 615106						False	3	100;0;0	1.15	True		ENSG00000204370	ENSG00000204370	HGNC:10683													
TMEM127	gene	TMEM127	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer; Paragangliomas 1, with or without deafness, 168000; Pheochromocytoma, 171300; Carcinoid tumors, intestinal, 114900; Merkel cell carcinoma, somatic; Paraganglioma and gastric stromal sarcoma, 606864; Cowden syndrome 3, 615106						False	3	100;0;0	1.15	True		ENSG00000135956	ENSG00000135956	HGNC:26038													
TP53	gene	TP53	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer; Paragangliomas 1, with or without deafness, 168000; Pheochromocytoma, 171300; Carcinoid tumors, intestinal, 114900; Merkel cell carcinoma, somatic; Paraganglioma and gastric stromal sarcoma, 606864; Cowden syndrome 3, 615106						False	3	100;0;0	1.15	True		ENSG00000141510	ENSG00000141510	HGNC:11998													
VHL	gene	VHL	Emory Genetics Laboratory;Expert Review Green	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer;Pheochromocytoma, OMIM:171300;von Hippel-Lindau syndrome, OMIM:193300;Paragangliomas, MONDO:0000448						False	3	100;0;0	1.15	True		ENSG00000134086	ENSG00000134086	HGNC:12687													
NTRK1	gene	NTRK1	Expert Review Red;Radboud University Medical Center, Nijmegen	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Insensitivity to pain, congenital, with anhidrosis, 256800; Medullary thyroid carcinoma, familial, 155240				PMID: 10443680		False	1	0;0;100	1.15	True		ENSG00000198400	ENSG00000198400	HGNC:8031													
PTEN	gene	PTEN	Emory Genetics Laboratory;Expert Review Red	Multiple endocrine tumours	Breast and endocrine	Tumour syndromes	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer						False	1	0;0;100	1.15	True		ENSG00000171862	ENSG00000171862	HGNC:9588