Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
CELA3B	gene	CELA3B	Expert Review Green;Literature	Pancreatitis		Gastrohepatology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Chronic Pancreatitis, MONDO:0005003;diabetes mellitus (disease), MONDO:0005015;Pancreatic cancer				31369399;33565216		False	3	100;0;0	3.5	False	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000219073	ENSG00000219073	HGNC:15945													
CFTR	gene	CFTR	EUROPAC;Expert Review Green;NHS GMS	Pancreatitis		Gastrohepatology	BIALLELIC, autosomal or pseudoautosomal	"{Pancreatitis, hereditary} 167800;Cystic fibrosis 	219700"				9725921;15987793;16134171;16193325;11729110;23951356;22427236;25033378;22658665;26856995;27555793;1345141;15749233;25033378;20977904;22427236		False	3	100;0;0	3.5	True		ENSG00000001626	ENSG00000001626	HGNC:1884													
PRSS1	gene	PRSS1	EUROPAC;Expert Review Green;NHS GMS	Pancreatitis		Gastrohepatology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Pancreatitis, hereditary 167800				8841182;10204851;10529393;11097832;11702203;15776435;16791840;18461367;17072318		False	3	100;0;0	3.5	True	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000204983	ENSG00000204983	HGNC:9475													
SPINK1	gene	SPINK1	EUROPAC;Expert Review Green;NHS GMS	Pancreatitis		Gastrohepatology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Pancreatitis, hereditary 167800				10835640;11355022;11938439;16823394;17274009;27535533		False	3	100;0;0	3.5	True		ENSG00000164266	ENSG00000164266	HGNC:11244													
CEL	gene	CEL	EUROPAC;Expert Review Amber	Pancreatitis		Gastrohepatology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Hereditary Pancreatitis				29233499;28881607;28500240;27802312;27650499;27773618;26946345;25774637;23770712;16369531;34850019		False	2	0;50;50	3.5	False		ENSG00000170835	ENSG00000170835	HGNC:1848													
CPA1	gene	CPA1	EUROPAC;Expert Review Amber;NHS GMS	Pancreatitis		Gastrohepatology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Chronic pancreatitis;Hereditary chronic pancreatitis				23955596;28497564;28258133;28650851		False	2	33;67;0	3.5	False		ENSG00000091704	ENSG00000091704	HGNC:2296													
CTRC	gene	CTRC	EUROPAC;Expert Review Amber;NHS GMS	Pancreatitis		Gastrohepatology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{Pancreatitis, chronic, susceptibility to} 167800				18059268;18172691;28502372		False	2	100;0;0	3.5	False		ENSG00000162438	ENSG00000162438	HGNC:2523													
KRT8	gene	KRT8	Expert Review Amber;NHS GMS	Pancreatitis		Gastrohepatology	BIALLELIC, autosomal or pseudoautosomal					29173301;27264265		False	2	0;100;0	3.5	False		ENSG00000170421	ENSG00000170421	HGNC:6446													
TRPV6	gene	TRPV6	Expert Review Amber;Literature	Pancreatitis		Gastrohepatology	BIALLELIC, autosomal or pseudoautosomal	Chronic pancreatitis				31930989;32383311		False	2	0;100;0	3.5	False		ENSG00000165125	ENSG00000165125	HGNC:14006													
CASR	gene	CASR	EUROPAC;NHS GMS	Pancreatitis		Gastrohepatology		Pancreatitis				29173301;17853337;26166472;18680227;20798521;18938753;16497624		False	1	0;67;33	3.5	False		ENSG00000036828	ENSG00000036828	HGNC:1514													
CCL2	gene	CCL2	EUROPAC	Pancreatitis		Gastrohepatology						25499426;22248664;23449669;21345872		False	1	0;0;100	3.5	False		ENSG00000108691	ENSG00000108691	HGNC:10618													
CLDN2	gene	CLDN2	EUROPAC	Pancreatitis		Gastrohepatology						29884332;29173301;28754779;26820620;26784911;26002935;25253127;23143602;28754779;24002981		False	1	0;0;100	3.5	False		ENSG00000165376	ENSG00000165376	HGNC:2041													
CTRB1	gene	CTRB1	EUROPAC	Pancreatitis		Gastrohepatology						28754779;28951524;30076839		False	1	0;0;100	3.5	False		ENSG00000168925	ENSG00000168925	HGNC:2521													
CTRB2	gene	CTRB2	EUROPAC	Pancreatitis		Gastrohepatology		risk factor for alcoholic and non-alcoholic chronic pancreatitis				28754779;28951524		False	1	0;0;100	3.5	False		ENSG00000168928	ENSG00000168928	HGNC:2522													
CTSB	gene	CTSB	EUROPAC;NHS GMS	Pancreatitis		Gastrohepatology						30455353;30134826;29229780;29079517;27226576;22580415;19900452;16492714;10995788		False	1	0;50;50	3.5	False		ENSG00000164733	ENSG00000164733	HGNC:2527													
CXCL8	gene	CXCL8	EUROPAC	Pancreatitis		Gastrohepatology								False	1	0;0;100	3.5	False		ENSG00000169429	ENSG00000169429	HGNC:6025													
MORC4	gene	MORC4	Literature	Pancreatitis		Gastrohepatology	Unknown					29884332;29173301;28754779;26820620;26784911;26002935;25253127;23143602;28754779;24002981		False	1	0;0;100	3.5	False		ENSG00000133131	ENSG00000133131	HGNC:23485													
PRSS2	gene	PRSS2	EUROPAC;NHS GMS	Pancreatitis		Gastrohepatology		"{Pancreatitis, chronic, protection against} 	167800"				25253127;23143602;27846138;26784911;26002935;26110235;29884332;19052022;15776435;16699518		False	1	0;50;50	3.5	False		-	ENSG00000275896	HGNC:9483