Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
APOA4	gene	APOA4	Expert Review Amber;Literature	Hereditary systemic amyloidosis		Renal	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Tubulointerstitial kidney disease, autosomal dominant 6, OMIM: 621106;tubulointerstitial kidney disease, autosomal dominant 6, MONDO:0976234;AApoAIV amyloidosis, MONDO:0018589				21900878;27262366;33751222;38096951;39699959		False	2	100;0;0	1.28	False		ENSG00000110244	ENSG00000110244	HGNC:602													
APOC3	gene	APOC3	Expert Review Amber;NHS GMS	Hereditary systemic amyloidosis		Renal	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted					26790392		False	2	100;0;0	1.28	False		ENSG00000110245	ENSG00000110245	HGNC:610													
B2M	gene	B2M	Expert Review Amber;NHS GMS	Hereditary systemic amyloidosis		Renal	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	?Amyloidosis, familial visceral 105200				22693999		False	2	100;0;0	1.28	False		ENSG00000166710	ENSG00000166710	HGNC:914													
CST3	gene	CST3	Expert Review Amber;NHS GMS	Hereditary systemic amyloidosis		Renal	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Cerebral amyloid angiopathy 105150				2900981;3495457;1352269;3673496;7482672		False	2	100;0;0	1.28	False		ENSG00000101439	ENSG00000101439	HGNC:2475													
NLRP3	gene	NLRP3	Expert list;Expert Review Amber	Hereditary systemic amyloidosis		Renal	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Muckle-Wells syndrome, OMIM:191900;Renal amyloidosis				11687797;28229991;27435956;31057541;30431487		False	2	100;0;0	1.28	False		ENSG00000162711	ENSG00000162711	HGNC:16400