Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ATM	gene	ATM	Expert Review Green;NHS GMS;Other	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Breast, prostate, pancreatic cancer predisposition;recessive trait for ataxia telangiectasia				34529012;33509806		False	3	100;0;0	3.2	False	Other	ENSG00000149311	ENSG00000149311	HGNC:795													
BRCA1	gene	BRCA1	Expert Review Green;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{Pancreatic cancer, susceptibility to, 4}, OMIM:614320;Pancreatic cancer, susceptibility to, 4, MONDO:0013685				30558719		False	3	67;33;0	3.2	False		ENSG00000012048	ENSG00000012048	HGNC:1100													
BRCA2	gene	BRCA2	Expert List;Expert Review Green;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{Pancreatic cancer 2}, OMIM:613347;Pancreatic cancer, susceptibility to, 2, MONDO:0013235				30558719		False	3	100;0;0	3.2	False		ENSG00000139618	ENSG00000139618	HGNC:1101													
CDKN2A	gene	CDKN2A	Expert List;Expert Review Green;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{Melanoma-pancreatic cancer syndrome}, OMIM:606719;Melanoma-pancreatic cancer syndrome, MONDO:0011713				30558719;32482799		False	3	100;0;0	3.2	False		ENSG00000147889	ENSG00000147889	HGNC:1787													
PALB2	gene	PALB2	Expert List;Expert Review Green;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{Pancreatic cancer, susceptibility to, 3}, OMIM:613348;Pancreatic cancer, susceptibility to, 3, MONDO:0013236				30558719		False	3	100;0;0	3.2	False		ENSG00000083093	ENSG00000083093	HGNC:26144													
STK11	gene	STK11	Expert Review Green;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Pancreatic cancer, somatic, OMIM:260350;familial pancreatic carcinoma, MONDO:0015278				30558719;33513864;11113065;16707622;23240097;23415580		False	3	100;0;0	3.2	False		ENSG00000118046	ENSG00000118046	HGNC:11389													
CDK4	gene	CDK4	Expert Review Amber;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Malignant pancreatic neoplasm, MONDO:0009831				30558719		False	2	100;0;0	3.2	False	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000135446	ENSG00000135446	HGNC:1773													
MLH1	gene	MLH1	Expert List;Expert Review Amber;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Malignant pancreatic neoplasm, MONDO:0009831				30558719		False	2	33;67;0	3.2	False		ENSG00000076242	ENSG00000076242	HGNC:7127													
MSH2	gene	MSH2	Expert List;Expert Review Amber;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Malignant pancreatic neoplasm, MONDO:0009831				30558719		False	2	33;67;0	3.2	False		ENSG00000095002	ENSG00000095002	HGNC:7325													
MSH6	gene	MSH6	Expert List;Expert Review Amber;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Malignant pancreatic neoplasm, MONDO:0009831				30558719		False	2	33;67;0	3.2	False		ENSG00000116062	ENSG00000116062	HGNC:7329													
PMS2	gene	PMS2	Expert List;Expert Review Amber;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Malignant pancreatic neoplasm, MONDO:0009831				30558719		False	2	33;67;0	3.2	False		ENSG00000122512	ENSG00000122512	HGNC:9122													
PRSS1	gene	PRSS1	Expert List;Expert Review Amber;NHS GMS	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Malignant pancreatic neoplasm, MONDO:0009831				30558719		False	2	50;50;0	3.2	False		ENSG00000204983	ENSG00000204983	HGNC:9475													
RABL3	gene	RABL3	Literature	Inherited pancreatic cancer		Inherited cancer	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	{?Pancreatic cancer, susceptibility to, 5}, OMIM:618680;Pancreatic cancer, susceptibility to, 5, MONDO:0032867				31406347		False	1	0;100;0	3.2	False		ENSG00000144840	ENSG00000144840	HGNC:18072