Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
AIP	gene	AIP	Expert Review Green;NHS GMS	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer;Pituitary adenoma, growth hormone-secreting, 102200;pituitary tumours;Familial Isolated Pituitary Adenomas;Pituitary adenoma, prolactin-secreting, 600634;Pituitary adenoma, ACTH-secreting, 219090						False	3	100;0;0	3.4	True		ENSG00000110711	ENSG00000110711	HGNC:358													
CDC73	gene	CDC73	Expert Review Green;NHS GMS	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer						False	3	100;0;0	3.4	True		ENSG00000134371	ENSG00000134371	HGNC:16783													
CDKN1B	gene	CDKN1B	Expert Review Green;NHS GMS	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Multiple endocrine neoplasia, type IV, OMIM:610755						False	3	100;0;0	3.4	True		ENSG00000111276	ENSG00000111276	HGNC:1785													
MEN1	gene	MEN1	Expert Review Green;NHS GMS	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer;pituitary tumours;Multiple Endocrine Neoplasia Type 1: MEN1 Gene Deletion/Duplication;Parathyroid adenoma, somatic;Multiple endocrine neoplasia 1, 131100;Carcinoid tumor of lung;Angiofibroma, somatic;Adrenal adenoma, somatic;Lipoma, somatic;MEN1-like spectrum;Multiple Endocrine Neoplasia						False	3	100;0;0	3.4	True		ENSG00000133895	ENSG00000133895	HGNC:7010													
PRKAR1A	gene	PRKAR1A	Expert Review;Expert Review Green	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Endocrine Cancer						False	3	0;100;0	3.4	False		ENSG00000108946	ENSG00000108946	HGNC:9388													
RET	gene	RET	Expert Review Green;NHS GMS	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	MEN2-like spectrum;Multiple Endocrine Neoplasia Type 2: RET Gene Deletion/Duplication;Multiple endocrine neoplasia IIA, 171400;Endocrine Cancer;Multiple Endocrine Neoplasia						False	3	100;0;0	3.4	True		ENSG00000165731	ENSG00000165731	HGNC:9967													
VHL	gene	VHL	Expert Review;Expert Review Green	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Endocrine Cancer;Paragangliomas 1, with or without deafness, 168000;Pheochromocytoma, 171300;Carcinoid tumors, intestinal, 114900;Merkel cell carcinoma, somatic;Paraganglioma and gastric stromal sarcoma, 606864;Cowden syndrome 3, 615106						False	3	0;100;0	3.4	False		ENSG00000134086	ENSG00000134086	HGNC:12687													
EGFR	gene	EGFR	Expert Review Amber;Literature	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Adrenocortical carcinoma				33326033		False	2	0;100;0	3.4	False		ENSG00000146648	ENSG00000146648	HGNC:3236													
MLH1	gene	MLH1	Expert list;Expert Review Amber	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown							False	2	0;100;0	3.4	False		ENSG00000076242	ENSG00000076242	HGNC:7127													
MSH2	gene	MSH2	Expert list;Expert Review Amber	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown							False	2	0;100;0	3.4	False		ENSG00000095002	ENSG00000095002	HGNC:7325													
MSH6	gene	MSH6	Expert list;Expert Review Amber	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown							False	2	0;100;0	3.4	False		ENSG00000116062	ENSG00000116062	HGNC:7329													
PMS2	gene	PMS2	Expert Review;Expert Review Amber	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown							False	2	0;100;0	3.4	False		ENSG00000122512	ENSG00000122512	HGNC:9122													
PTEN	gene	PTEN	Expert list;Expert Review Amber	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown							False	2	0;100;0	3.4	False		ENSG00000171862	ENSG00000171862	HGNC:9588													
TP53	gene	TP53	Expert Review;Expert Review Amber	Endocrine neoplasia		Endocrinology	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Endocrine Cancer;Paragangliomas 1, with or without deafness, 168000;Pheochromocytoma, 171300;Carcinoid tumors, intestinal, 114900;Merkel cell carcinoma, somatic;Paraganglioma and gastric stromal sarcoma, 606864;Cowden syndrome 3, 615106						False	2	0;100;0	3.4	False		ENSG00000141510	ENSG00000141510	HGNC:11998