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| COVID-19 research v0.36 | C4B |
Ellen McDonagh gene: C4B was added gene: C4B was added to Viral susceptibility. Sources: Expert Review Green,Victorian Clinical Genetics Services,North West GLH,GRID V2.0,NHS GMS,London North GLH,IUIS Classification February 2018 Mode of inheritance for gene: C4B was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: C4B were set to 12626442; 2355198; 19062096; 1569346; 2788199 Phenotypes for gene: C4B were set to C4B deficiency, 614379; SLE, infections with encapsulated organisms , partial deficiency is common (either C4A or C4B) and appears to have a modest effect on host defense; Complement Deficiencies; SLE predisposition |
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| COVID-19 research v0.36 | C4A |
Ellen McDonagh gene: C4A was added gene: C4A was added to Viral susceptibility. Sources: Expert Review Green,ESID Registry 20171117,North West GLH,Victorian Clinical Genetics Services,GRID V2.0,NHS GMS,London North GLH,IUIS Classification February 2018 Mode of inheritance for gene: C4A was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: C4A were set to 15294999; 2295875; 22482068 Phenotypes for gene: C4A were set to C4a deficiency, 614380; Complement Deficiencies; SLE, infections with encapsulated organisms , partial deficiency is common (either C4A or C4B) and appears to have a modest effect on host defense; Complement component 4 deficiency; SLE predisposition; Immunodeficiency due to a classical component pathway complement deficiency; infections with encapsulated organisms |
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