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| COVID-19 research v1.134 | DDX58 | Eleanor Williams commented on gene: DDX58 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v1.134 | DDX58 | Eleanor Williams Tag new-gene-name tag was added to gene: DDX58. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.223 | DDX58 | Sarah Leigh Classified gene: DDX58 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.223 | DDX58 | Sarah Leigh Added comment: Comment on list classification: Wild type DDX58 confers detection and eradication of replicating viral genomes, variants in this gene could therefore interfere with this mechanism. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.223 | DDX58 | Sarah Leigh Gene: ddx58 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.222 | DDX58 | Sarah Leigh Publications for gene: DDX58 were set to 21939710; 16625202 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| COVID-19 research v0.221 | DDX58 |
Sarah Leigh gene: DDX58 was added gene: DDX58 was added to Viral susceptibility. Sources: Literature Mode of inheritance for gene: DDX58 was set to Unknown Publications for gene: DDX58 were set to 21939710; 16625202 Added comment: PMID 21939710 found DDX5 (formerly known as RIGI) was essential for virus-induced expression of IRF3 and concluded that DDX5 is essential for detection and eradication of replicating viral genomes. PMID 16625202 reported that DDX58 is essential for the production of interferons in response to certain RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus. Sources: Literature |
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