Activity

Filter

Cancel
Date Panel Item Activity
4 actions
COVID-19 research v0.347 ITGAV Alison Coffey commented on gene: ITGAV: Evidence Summary from Illumina curation team: ITGAV or ALPHA-V is a component of the integrin family of transmembrane proteins. Integrins primary biological functions involve cell adhesion and migration, organization of the cytoskeleton, and other cellular functions. Alpha-V-containing integrins combine an alpha-V subunit with 1 of 5 beta subunits. Several families of viruses are known to use alpha-V-containing integrins for cell attachment and entry, including human adenovirus type 2/5, human CMV, HIV-1, EBV, rotavirus, Coxsackievirus, and Ebola virus (Hussein et al. 2015; LaFoya et al. 2018).
COVID-19 research v0.341 ITGAV Alison Coffey reviewed gene: ITGAV: Rating: GREEN; Mode of pathogenicity: ; Publications: 29393909, 26321473; Phenotypes: ; Mode of inheritance:
COVID-19 research v0.336 ITGAV Rebecca Foulger commented on gene: ITGAV
COVID-19 research v0.333 ITGAV Rebecca Foulger gene: ITGAV was added
gene: ITGAV was added to COVID-19 research. Sources: Expert list,OMIM,Expert Review Green
Mode of inheritance for gene: ITGAV was set to Unknown