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COVID-19 research v0.83 | NFKBID | Sarah Leigh Classified gene: NFKBID as Red List (low evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
COVID-19 research v0.83 | NFKBID | Sarah Leigh Added comment: Comment on list classification: Not associated with phenotype in OMIM or in Gen2Phen. The only variants are structural rearrangements that include NFKBID amongst other genes. PMID 26973645 reports "heterozygous mutation in the nfkbid gene encoding the atypical IκB protein IκBNS led to reduced steady state IgM and IgG3 antibody levels and impaired response to vaccination with TI-2 antigens in mice". Thus, variants in human NFKBID may also result in reduced levels of IgM and IgG3 and compromized vaccination responses. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
COVID-19 research v0.83 | NFKBID | Sarah Leigh Gene: nfkbid has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
COVID-19 research v0.82 | NFKBID | Sarah Leigh Publications for gene: NFKBID were set to | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
COVID-19 research v0.36 | NFKBID |
Ellen McDonagh gene: NFKBID was added gene: NFKBID was added to Viral susceptibility. Sources: Expert Review Red,Victorian Clinical Genetics Services Mode of inheritance for gene: NFKBID was set to Unknown |