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| COVID-19 research v0.293 | NRP2 |
Eleanor Williams gene: NRP2 was added gene: NRP2 was added to COVID-19 research. Sources: Literature Mode of inheritance for gene: NRP2 was set to Unknown Publications for gene: NRP2 were set to 30057110; 29120745 Review for gene: NRP2 was set to RED Added comment: Not associated with a disease phenotype in OMIM or Gene2Phenotype. PMID: 30057110: Martinez-Martin et al. (2018) identified NRP2 as a host receptor for human cytomegalovirus (HCMV) pentamer. PMID: 29120745 -Raaben et al 2017 - A genome-wide haploid genetic screen identified the transmembrane protein neuropilin 2 (NRP2) and tetraspanin CD63 as factors for Lujo virus (LUJV) glycoprotein-mediated infection. Overexpression of NRP2 or its N-terminal domain enhances VSV-LUJV infection, and cells lacking NRP2 are deficient in wild-type LUJV infection. Sources: Literature |
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