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COVID-19 research v0.319 | STAT6 |
Ivone Leong gene: STAT6 was added gene: STAT6 was added to COVID-19 research. Sources: Expert list Mode of inheritance for gene: STAT6 was set to Unknown Publications for gene: STAT6 were set to 22000020; 21762972 Review for gene: STAT6 was set to RED Added comment: Immune system gene: STAT6 mediates immune signaling in response to cytokines at the plasma membrane and to virus infection at the endoplasmic reticulum. Mice lacking Stat6 were susceptible to virus infection. Chen et al. (2011) (PMID: 22000020). PMID: 21762972 found that STAT6 increases viral replication in the skin of patients with atopic dermatitis (chronic inflammatory skin disease) with a history of eczema herpeticum. Sources: Expert list |