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Arrhythmogenic right ventricular cardiomyopathy v1.45 DSG2 Ivone Leong reviewed gene: DSG2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Arrhythmogenic right ventricular cardiomyopathy v1.36 DSG2 Matthew Edwards reviewed gene: DSG2: Rating: GREEN; Mode of pathogenicity: None; Publications: 29567486; Phenotypes: OMIM: 610193 Arrhythmogenic right ventricular dysplasia 10; Mode of inheritance: None; Current diagnostic: yes
Arrhythmogenic right ventricular cardiomyopathy v1.36 DSG2 Matthew Edwards Deleted their review
Arrhythmogenic right ventricular cardiomyopathy v1.36 DSG2 Matthew Edwards changed review comment from: On CGGL royal Brompton ACM panel. Definitive ARVC gene.; to: On CGGL royal Brompton ACM panel. Definitive ARVC gene.
Arrhythmogenic right ventricular cardiomyopathy v1.36 DSG2 Matthew Edwards reviewed gene: DSG2: Rating: ; Mode of pathogenicity: None; Publications: 29567486; Phenotypes: OMIM: 610193 Arrhythmogenic right ventricular dysplasia 10; Mode of inheritance: None; Current diagnostic: yes
Arrhythmogenic right ventricular cardiomyopathy v1.35 DSG2 Ivone Leong Publications for gene: DSG2 were set to 27532257; 23500315
Arrhythmogenic right ventricular cardiomyopathy v1.23 DSG2 Rebecca Whittington commented on gene: DSG2: Arrhythmogenic right ventricular dysplasia 10 (610193); Cardiomyopathy, dilated, 1BB (612877)
Arrhythmogenic right ventricular cardiomyopathy v1.22 DSG2 Rebecca Whittington commented on gene: DSG2: PubMED: 29567486 - core gene. Lots of entries on HGMDPro for ARVC - including good evidence. One C4 reported at BGL.
Arrhythmogenic right ventricular cardiomyopathy v1.21 DSG2 Rebecca Whittington reviewed gene: DSG2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted; Current diagnostic: yes
Arrhythmogenic right ventricular cardiomyopathy v1.20 DSG2 Ellen McDonagh Source South West GLH was added to DSG2.
Mode of inheritance for gene DSG2 was changed from MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Arrhythmogenic right ventricular cardiomyopathy v1.19 DSG2 Ellen McDonagh reviewed gene: DSG2: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Arrhythmogenic right ventricular cardiomyopathy v1.18 DSG2 Ellen McDonagh Source London South GLH was added to DSG2.
Arrhythmogenic right ventricular cardiomyopathy v1.17 DSG2 James Eden reviewed gene: DSG2: Rating: GREEN; Mode of pathogenicity: ; Publications: 23500315, 27532257; Phenotypes: Arrhythmogenic right ventricular dysplasia 10 (610193), Cardiomyopathy, dilated, 1BB (612877); Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown; Current diagnostic: yes
Arrhythmogenic right ventricular cardiomyopathy v1.16 DSG2 Ellen McDonagh Source North West GLH was added to DSG2.
Added phenotypes Cardiomyopathy, dilated, 1BB (612877); Arrhythmogenic right ventricular dysplasia 10 (610193) for gene: DSG2
Publications for gene DSG2 were changed from to 27532257; 23500315
Rating Changed from Green List (high evidence) to Green List (high evidence)