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Hereditary spastic paraplegia v1.248 REEP2 Arina Puzriakova Classified gene: REEP2 as Green List (high evidence)
Hereditary spastic paraplegia v1.248 REEP2 Arina Puzriakova Added comment: Comment on list classification: Upgraded from Amber to Green as there are now sufficient unrelated cases (>3) of spasticity associated with variants in this gene (updated references in publications list). REEP2 is also already Green on the GMS-equivalent HSP panels.
Hereditary spastic paraplegia v1.248 REEP2 Arina Puzriakova Gene: reep2 has been classified as Green List (High Evidence).
Hereditary spastic paraplegia v1.247 REEP2 Arina Puzriakova Publications for gene: REEP2 were set to 24388663
Hereditary spastic paraplegia v1.203 REEP2 Louise Daugherty Deleted their comment
Hereditary spastic paraplegia v1.203 REEP2 Louise Daugherty commented on gene: REEP2: Gene to be reviewed again after the GMS Neurology specialist test group have reviewed and agreed rating of gene on the Hereditary spastic paraplegia - childhood onset panel on May 2019
Hereditary spastic paraplegia v1.203 REEP2 Louise Daugherty edited their review of gene: REEP2: Added comment: Gene to be reviewed again after the GMS Neurology specialist test group have reviewed and agreed rating of gene on the Hereditary spastic paraplegia - childhood onset panel on May 2019; Changed rating: AMBER
Hereditary spastic paraplegia v1.71 REEP2 Chris Buxton edited their review of gene: REEP2: Changed mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Hereditary spastic paraplegia v1.71 REEP2 Chris Buxton reviewed gene: REEP2: Rating: AMBER; Mode of pathogenicity: None; Publications: 28491902; Phenotypes: spastic paprplegia; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Hereditary spastic paraplegia REEP2 Louise Daugherty classified REEP2 as Amber List (moderate evidence)
Hereditary spastic paraplegia REEP2 Louise Daugherty Added gene to panel