06 Sep 2021
Rare syndromic craniosynostosis or isolated multisuture synostosis v2.52
JAG1
Arina Puzriakova Phenotypes for gene: JAG1 were changed from Alagille syndrome to Alagille syndrome 1, OMIM:118450
11 Jun 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.122
JAG1
Eleanor Williams Mode of inheritance for gene: JAG1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
21 May 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.87
JAG1
Eleanor Williams Classified gene: JAG1 as Green List (high evidence)
21 May 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.87
JAG1
Eleanor Williams Added comment: Comment on list classification: Upgrading from red to green. Green rating agreed at the GMS musculoskeletal specialist test group Webex on 2019-05-13.
21 May 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.87
JAG1
Eleanor Williams Gene: jag1 has been classified as Green List (High Evidence).
11 May 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.72
JAG1
Eleanor Williams Added phenotypes Alagille syndrome for gene: JAG1
02 May 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.61
JAG1
Eleanor Williams Added comment: Comment on publications: Adding PMID: 29530693 - Narro-Donate et al 2018
02 May 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.61
JAG1
Eleanor Williams Publications for gene: JAG1 were set to
05 Mar 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.47
JAG1
Tracy Lester reviewed gene: JAG1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: Alagille syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
05 Mar 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.46
JAG1
Eleanor Williams reviewed gene: JAG1: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
05 Mar 2019
Rare syndromic craniosynostosis or isolated multisuture synostosis v1.45
JAG1
Eleanor Williams Source NHS GMS was added to JAG1.