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Date	Panel	Item	Activity
Filter activities 28 actions
16 Oct 2023	Intellectual disability - microarray and sequencing v5.313	PLK1	Eleanor Williams Tag gene-checked tag was added to gene: PLK1.
16 Oct 2023	Intellectual disability - microarray and sequencing v5.313	PLK1	Eleanor Williams commented on gene: PLK1
11 Oct 2023	Intellectual disability - microarray and sequencing v5.299	PLK1	Arina Puzriakova Tag Q2_23_promote_green was removed from gene: PLK1.
11 Oct 2023	Intellectual disability - microarray and sequencing v5.286	PLK1	Arina Puzriakova reviewed gene: PLK1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
11 Oct 2023	Intellectual disability - microarray and sequencing v5.286	PLK1	Arina Puzriakova Source NHS GMS was added to PLK1. Source Expert Review Green was added to PLK1. Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
21 Apr 2023	Intellectual disability - microarray and sequencing v5.67	PLK1	Achchuthan Shanmugasundram Deleted their comment
21 Apr 2023	Intellectual disability - microarray and sequencing v5.67	PLK1	Achchuthan Shanmugasundram Deleted their comment
21 Apr 2023	Intellectual disability - microarray and sequencing v5.67	PLK1	Achchuthan Shanmugasundram Deleted their comment
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Classified gene: PLK1 as Amber List (moderate evidence)
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Dmitrijs Rots (RadboudUMC), there is sufficient evidence for this gene to be promoted to GREEN at the next major review.
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Gene: plk1 has been classified as Amber List (Moderate Evidence).
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Classified gene: PLK1 as Amber List (moderate evidence)
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Dmitrijs Rots (RadboudUMC), there is sufficient evidence for this gene to be promoted to GREEN at the next major review.
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Gene: plk1 has been classified as Amber List (Moderate Evidence).
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Classified gene: PLK1 as Amber List (moderate evidence)
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Dmitrijs Rots (RadboudUMC), there is sufficient evidence for this gene to be promoted to GREEN at the next major review.
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Gene: plk1 has been classified as Amber List (Moderate Evidence).
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Classified gene: PLK1 as Amber List (moderate evidence)
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Dmitrijs Rots (RadboudUMC), there is sufficient evidence for this gene to be promoted to GREEN at the next major review.
17 Apr 2023	Intellectual disability - microarray and sequencing v5.53	PLK1	Achchuthan Shanmugasundram Gene: plk1 has been classified as Amber List (Moderate Evidence).
17 Apr 2023	Intellectual disability - microarray and sequencing v5.52	PLK1	Achchuthan Shanmugasundram Publications for gene: PLK1 were set to 33875846
17 Apr 2023	Intellectual disability - microarray and sequencing v5.52	PLK1	Achchuthan Shanmugasundram Publications for gene: PLK1 were set to 33875846
17 Apr 2023	Intellectual disability - microarray and sequencing v5.52	PLK1	Achchuthan Shanmugasundram Publications for gene: PLK1 were set to 33875846
17 Apr 2023	Intellectual disability - microarray and sequencing v5.51	PLK1	Achchuthan Shanmugasundram Publications for gene: PLK1 were set to 33875846
17 Apr 2023	Intellectual disability - microarray and sequencing v5.51	PLK1	Achchuthan Shanmugasundram Publications for gene: PLK1 were set to PMID: 33875846
17 Apr 2023	Intellectual disability - microarray and sequencing v5.50	PLK1	Achchuthan Shanmugasundram Tag Q2_23_promote_green tag was added to gene: PLK1.
17 Apr 2023	Intellectual disability - microarray and sequencing v5.50	PLK1	Achchuthan Shanmugasundram reviewed gene: PLK1: Rating: GREEN; Mode of pathogenicity: None; Publications: 33875846; Phenotypes: intellectual disability, MONDO:0001071; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
30 Oct 2021	Intellectual disability - microarray and sequencing v3.1396	PLK1	Dmitrijs Rots gene: PLK1 was added gene: PLK1 was added to Intellectual disability. Sources: Literature Mode of inheritance for gene: PLK1 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: PLK1 were set to PMID: 33875846 Phenotypes for gene: PLK1 were set to Epilepsy; microcephaly; intellectual disability Review for gene: PLK1 was set to GREEN Added comment: >5 cases with epileptic encephalopathy with homozygous variants in PMID: 33875846 Sources: Literature