Activity

Filter

Cancel
Date Panel Item Activity
27 actions
Primary immunodeficiency or monogenic inflammatory bowel disease v2.229 CASP8 Eleanor Williams Classified gene: CASP8 as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.229 CASP8 Eleanor Williams Added comment: Comment on list classification: Changed rating of gene from Red to Green. This gene was rated as Green in v2.208 and incorrectly automatically demoted to Red in v2.209. This was due to a defect in the automatic PanelApp uploading tool when a set of publications was added to the panel with the source ‘Other’, and under certain conditions associated to previous sources listed, resulted in the rating of the gene being automatically changed when it should not have been.
Primary immunodeficiency or monogenic inflammatory bowel disease v2.229 CASP8 Eleanor Williams Gene: casp8 has been classified as Green List (High Evidence).
Primary immunodeficiency or monogenic inflammatory bowel disease v2.209 CASP8 Eleanor Williams Source Other was added to CASP8.
Publications for gene CASP8 were updated from 12353035; 16157684; 24240292; 20301287 to 12353035; 20301287; 16157684; 24240292; 15492869
Rating Changed from Green List (high evidence) to Red List (low evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.208 CASP8 Eleanor Williams reviewed gene: CASP8: Rating: ; Mode of pathogenicity: ; Publications: 12353035, 15492869; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 CASP8 Louise Daugherty commented on gene: CASP8: Gene rating submitted by Kimberly Gilmour and Austen Worth on behalf of London North GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email 6th September the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 CASP8 Louise Daugherty commented on gene: CASP8: Gene rating submitted by Tracy Briggs, David Gokhale and Abigal Rousseau on behalf of North West GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email on 20th June the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 CASP8 Kimberly Gilmour reviewed gene: CASP8: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 CASP8 Tracy Briggs reviewed gene: CASP8: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.60 CASP8 Louise Daugherty Source NHS GMS was added to CASP8.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.59 CASP8 Louise Daugherty Source North West GLH was added to CASP8.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.58 CASP8 Louise Daugherty Source London North GLH was added to CASP8.
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of gene: CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty marked gene: CASP8 as ready
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty classified CASP8 as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Sophie Hambleton reviewed gene: CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty edited their review of CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty commented on CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty commented on CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty commented on CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty reviewed CASP8
Primary immunodeficiency or monogenic inflammatory bowel disease CASP8 Louise Daugherty Added gene to panel