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Primary immunodeficiency or monogenic inflammatory bowel disease v2.300 RAB27A Eleanor Williams Classified gene: RAB27A as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.300 RAB27A Eleanor Williams Added comment: Comment on list classification: Changed rating of gene from Red to Green. This gene was rated as Green in v2.208 and incorrectly automatically demoted to Red in v2.209. This was due to a defect in the automatic PanelApp uploading tool when a set of publications was added to the panel with the source ‘Other’, and under certain conditions associated to previous sources listed, resulted in the rating of the gene being automatically changed when it should not have been.
Primary immunodeficiency or monogenic inflammatory bowel disease v2.300 RAB27A Eleanor Williams Gene: rab27a has been classified as Green List (High Evidence).
Primary immunodeficiency or monogenic inflammatory bowel disease v2.209 RAB27A Eleanor Williams Source Other was added to RAB27A.
Publications for gene RAB27A were updated from 12058346; 12531900; 12522785; 15163896; 15163896 to 12531900; 9486701; 12058346; 10835631; 24134793; 12522785; 15163896; 16517541
Rating Changed from Green List (high evidence) to Red List (low evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.208 RAB27A Eleanor Williams reviewed gene: RAB27A: Rating: ; Mode of pathogenicity: ; Publications: 24134793, 10835631, 16517541, 9486701; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 RAB27A Louise Daugherty commented on gene: RAB27A: Gene rating submitted by Kimberly Gilmour and Austen Worth on behalf of London North GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email 6th September the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 RAB27A Louise Daugherty commented on gene: RAB27A: Gene rating submitted by Tracy Briggs, David Gokhale and Abigal Rousseau on behalf of North West GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email on 20th June the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 RAB27A Kimberly Gilmour reviewed gene: RAB27A: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 RAB27A Tracy Briggs reviewed gene: RAB27A: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.60 RAB27A Louise Daugherty Source NHS GMS was added to RAB27A.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.59 RAB27A Louise Daugherty Source North West GLH was added to RAB27A.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.58 RAB27A Louise Daugherty Source London North GLH was added to RAB27A.
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty edited their review of gene: RAB27A
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty marked gene: RAB27A as ready
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Sophie Hambleton reviewed gene: RAB27A
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Sarah Leigh classified RAB27A as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty commented on RAB27A
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty commented on RAB27A
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty commented on RAB27A
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty reviewed RAB27A
Primary immunodeficiency or monogenic inflammatory bowel disease RAB27A Louise Daugherty Added gene to panel