08 Oct 2019
Early onset or syndromic epilepsy v1.360
CCND2
Rebecca Foulger Marked gene: CCND2 as ready
08 Oct 2019
Early onset or syndromic epilepsy v1.360
CCND2
Rebecca Foulger Gene: ccnd2 has been classified as Red List (Low Evidence).
08 Oct 2019
Early onset or syndromic epilepsy v1.360
CCND2
Rebecca Foulger Classified gene: CCND2 as Red List (low evidence)
08 Oct 2019
Early onset or syndromic epilepsy v1.360
CCND2
Rebecca Foulger Added comment: Comment on list classification: Demoted CCND2 from Amber to Red following Red reviews by Zornitza Stark and Tracy Lester- as noted previously by Sarah Leigh: epilepsy is not a reported feature of the disorder.
08 Oct 2019
Early onset or syndromic epilepsy v1.360
CCND2
Rebecca Foulger Gene: ccnd2 has been classified as Red List (Low Evidence).
08 Oct 2019
Early onset or syndromic epilepsy v1.359
CCND2
Rebecca Foulger Mode of inheritance for gene: CCND2 was changed from to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
08 Oct 2019
Early onset or syndromic epilepsy v1.358
CCND2
Rebecca Foulger Publications for gene: CCND2 were set to
08 Oct 2019
Early onset or syndromic epilepsy v1.357
CCND2
Rebecca Foulger Phenotypes for gene: CCND2 were changed from to Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3, 615938
06 Aug 2019
Early onset or syndromic epilepsy v1.191
CCND2
Rebecca Foulger Source Wessex and West Midlands GLH was added to CCND2.
06 Aug 2019
Early onset or syndromic epilepsy v1.190
CCND2
Rebecca Foulger Source NHS GMS was added to CCND2.
06 Aug 2019
Early onset or syndromic epilepsy v1.189
CCND2
Rebecca Foulger reviewed gene: CCND2: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
06 Aug 2019
Early onset or syndromic epilepsy v1.188
CCND2
Tracy Lester reviewed gene: CCND2: Rating: RED; Mode of pathogenicity: ; Publications: 24705253; Phenotypes: Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3, 615938; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
01 Oct 2018
Early onset or syndromic epilepsy v0.499
CCND2
Sarah Leigh Marked gene: CCND2 as ready
01 Oct 2018
Early onset or syndromic epilepsy v0.499
CCND2
Sarah Leigh Added comment: Comment when marking as ready: Phenotype does not include seizures and to this gene is not relevant to the Genetic epilepsy syndromes panel.
01 Oct 2018
Early onset or syndromic epilepsy v0.499
CCND2
Sarah Leigh Gene: ccnd2 has been classified as Amber List (Moderate Evidence).
10 Aug 2018
Early onset or syndromic epilepsy
CCND2
Zornitza Stark reviewed gene: CCND2
25 Jun 2018
Early onset or syndromic epilepsy
CCND2
Sarah Leigh Added gene to panel