03 Aug 2021
Early onset or syndromic epilepsy v2.401
COQ2
Ivone Leong Phenotypes for gene: COQ2 were changed from Coenzyme Q10 deficiency, primary, 1 607426 to Coenzyme Q10 deficiency, primary, 1, OMIM:607426
06 Aug 2019
Early onset or syndromic epilepsy v1.191
COQ2
Rebecca Foulger Source Wessex and West Midlands GLH was added to COQ2.
06 Aug 2019
Early onset or syndromic epilepsy v1.190
COQ2
Rebecca Foulger Source NHS GMS was added to COQ2.
06 Aug 2019
Early onset or syndromic epilepsy v1.189
COQ2
Rebecca Foulger reviewed gene: COQ2: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
06 Aug 2019
Early onset or syndromic epilepsy v1.188
COQ2
Tracy Lester reviewed gene: COQ2: Rating: GREEN; Mode of pathogenicity: ; Publications: 17855635; Phenotypes: Coenzyme Q10 deficiency primary, 607426; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
13 Nov 2018
Early onset or syndromic epilepsy v0.800
COQ2
Sarah Leigh Marked gene: COQ2 as ready
13 Nov 2018
Early onset or syndromic epilepsy v0.800
COQ2
Sarah Leigh Added comment: Comment when marking as ready: Associated with relevant phenotype in OMIM and as confirmed Gen2Phen gene. At least 3 variants reported in unrelated cases in which seizures are a phenotypic feature.
13 Nov 2018
Early onset or syndromic epilepsy v0.800
COQ2
Sarah Leigh Gene: coq2 has been classified as Green List (High Evidence).
13 Nov 2018
Early onset or syndromic epilepsy v0.800
COQ2
Sarah Leigh Classified gene: COQ2 as Green List (high evidence)
13 Nov 2018
Early onset or syndromic epilepsy v0.800
COQ2
Sarah Leigh Gene: coq2 has been classified as Green List (High Evidence).
13 Nov 2018
Early onset or syndromic epilepsy v0.799
COQ2
Sarah Leigh Publications for gene: COQ2 were set to
13 Nov 2018
Early onset or syndromic epilepsy v0.797
COQ2
Sarah Leigh Phenotypes for gene: COQ2 were changed from to Coenzyme Q10 deficiency, primary, 1 607426
13 Nov 2018
Early onset or syndromic epilepsy v0.796
COQ2
Sarah Leigh Mode of inheritance for gene: COQ2 was changed from to BIALLELIC, autosomal or pseudoautosomal
12 Aug 2018
Early onset or syndromic epilepsy
COQ2
Zornitza Stark reviewed gene: COQ2
25 Jun 2018
Early onset or syndromic epilepsy
COQ2
Sarah Leigh Added gene to panel