06 Aug 2019
Early onset or syndromic epilepsy v1.191
PIGO
Rebecca Foulger Source Wessex and West Midlands GLH was added to PIGO.
06 Aug 2019
Early onset or syndromic epilepsy v1.190
PIGO
Rebecca Foulger Source NHS GMS was added to PIGO.
06 Aug 2019
Early onset or syndromic epilepsy v1.189
PIGO
Rebecca Foulger reviewed gene: PIGO: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
06 Aug 2019
Early onset or syndromic epilepsy v1.188
PIGO
Tracy Lester reviewed gene: PIGO: Rating: GREEN; Mode of pathogenicity: ; Publications: 22683086; Phenotypes: Hyperphosphatasia with mental retardation syndrome, 614749; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
21 Nov 2018
Early onset or syndromic epilepsy v0.1028
PIGO
Eleanor Williams Marked gene: PIGO as ready
21 Nov 2018
Early onset or syndromic epilepsy v0.1028
PIGO
Eleanor Williams Added comment: Comment when marking as ready: Sufficient cases with compound heterozygous mutations in PIGO and 3 cases with seizures.
21 Nov 2018
Early onset or syndromic epilepsy v0.1028
PIGO
Eleanor Williams Gene: pigo has been classified as Green List (High Evidence).
21 Nov 2018
Early onset or syndromic epilepsy v0.1028
PIGO
Eleanor Williams Publications for gene: PIGO were set to 22683086; 24049131; 24417746; 28900819
21 Nov 2018
Early onset or syndromic epilepsy v0.1027
PIGO
Eleanor Williams Phenotypes for gene: PIGO were changed from to Hyperphosphatasia with mental retardation syndrome 2, 614749
21 Nov 2018
Early onset or syndromic epilepsy v0.1026
PIGO
Eleanor Williams Added comment: Comment on publications: Further cases reported in PMIDs: 28900819 and 28337824
21 Nov 2018
Early onset or syndromic epilepsy v0.1026
PIGO
Eleanor Williams Publications for gene: PIGO were set to
21 Nov 2018
Early onset or syndromic epilepsy v0.1025
PIGO
Eleanor Williams Mode of inheritance for gene: PIGO was changed from to BIALLELIC, autosomal or pseudoautosomal
21 Nov 2018
Early onset or syndromic epilepsy v0.1024
PIGO
Eleanor Williams Classified gene: PIGO as Green List (high evidence)
21 Nov 2018
Early onset or syndromic epilepsy v0.1024
PIGO
Eleanor Williams Added comment: Comment on list classification: Sufficient cases with compound heterogzyous mutations in PIGO and 3 cases with seizures.
21 Nov 2018
Early onset or syndromic epilepsy v0.1024
PIGO
Eleanor Williams Gene: pigo has been classified as Green List (High Evidence).
21 Nov 2018
Early onset or syndromic epilepsy v0.1023
PIGO
Eleanor Williams commented on gene: PIGO
18 Aug 2018
Early onset or syndromic epilepsy
PIGO
Zornitza Stark reviewed gene: PIGO
25 Jun 2018
Early onset or syndromic epilepsy
PIGO
Sarah Leigh Added gene to panel