06 Aug 2019
Early onset or syndromic epilepsy v1.191
PIGW
Rebecca Foulger Source Wessex and West Midlands GLH was added to PIGW.
06 Aug 2019
Early onset or syndromic epilepsy v1.190
PIGW
Rebecca Foulger Source NHS GMS was added to PIGW.
06 Aug 2019
Early onset or syndromic epilepsy v1.189
PIGW
Rebecca Foulger reviewed gene: PIGW: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
06 Aug 2019
Early onset or syndromic epilepsy v1.188
PIGW
Tracy Lester reviewed gene: PIGW: Rating: GREEN; Mode of pathogenicity: ; Publications: 27626616; Phenotypes: Glycosylphosphatidylinositol biosynthesis defect, 616025; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
21 Nov 2018
Early onset or syndromic epilepsy v0.1034
PIGW
Eleanor Williams Marked gene: PIGW as ready
21 Nov 2018
Early onset or syndromic epilepsy v0.1034
PIGW
Eleanor Williams Added comment: Comment when marking as ready: Sufficient cases to make green
21 Nov 2018
Early onset or syndromic epilepsy v0.1034
PIGW
Eleanor Williams Gene: pigw has been classified as Green List (High Evidence).
21 Nov 2018
Early onset or syndromic epilepsy v0.1034
PIGW
Eleanor Williams Phenotypes for gene: PIGW were changed from to Glycosylphosphatidylinositol biosynthesis defect 11, 616025; HYPERPHOSPHATASIA WITH MENTAL RETARDATION SYNDROME 5
21 Nov 2018
Early onset or syndromic epilepsy v0.1033
PIGW
Eleanor Williams Publications for gene: PIGW were set to 24367057; 27626616; 30078644
21 Nov 2018
Early onset or syndromic epilepsy v0.1032
PIGW
Eleanor Williams Publications for gene: PIGW were set to
21 Nov 2018
Early onset or syndromic epilepsy v0.1030
PIGW
Eleanor Williams Mode of inheritance for gene: PIGW was changed from to BIALLELIC, autosomal or pseudoautosomal
21 Nov 2018
Early onset or syndromic epilepsy v0.1029
PIGW
Eleanor Williams Classified gene: PIGW as Green List (high evidence)
21 Nov 2018
Early onset or syndromic epilepsy v0.1029
PIGW
Eleanor Williams Added comment: Comment on list classification: 3 cases/families reported, all with seizures
21 Nov 2018
Early onset or syndromic epilepsy v0.1029
PIGW
Eleanor Williams Gene: pigw has been classified as Green List (High Evidence).
21 Nov 2018
Early onset or syndromic epilepsy v0.1028
PIGW
Eleanor Williams commented on gene: PIGW
16 Oct 2018
Early onset or syndromic epilepsy v0.505
PIGW
Konstantinos Varvagiannis reviewed gene: PIGW: Rating: GREEN; Mode of pathogenicity: None; Publications: 30078644; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal; Current diagnostic: yes
19 Aug 2018
Early onset or syndromic epilepsy
PIGW
Zornitza Stark reviewed gene: PIGW
25 Jun 2018
Early onset or syndromic epilepsy
PIGW
Sarah Leigh Added gene to panel