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Dilated Cardiomyopathy and conduction defects v1.65 FKTN Ivone Leong Classified gene: FKTN as Amber List (moderate evidence)
Dilated Cardiomyopathy and conduction defects v1.65 FKTN Ivone Leong Added comment: Comment on list classification: Demoted from Green to Amber based on the expert reviews and also based on the gene rating on Dilated cardiomyopathy - adult and teen (version 1.0) which has been signed off by the GMS cardiology specialist group.
Dilated Cardiomyopathy and conduction defects v1.65 FKTN Ivone Leong Gene: fktn has been classified as Amber List (Moderate Evidence).
Dilated Cardiomyopathy and conduction defects v1.55 FKTN Matthew Edwards reviewed gene: FKTN: Rating: RED; Mode of pathogenicity: None; Publications: 17878207, 18177472, 18752264 , 19266496, 27065010; Phenotypes: Walker-Warburg syndrome (WWS), Fukuyama congenital muscular dystrophy, Cardiomyopathy, dilated, 1X; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Dilated Cardiomyopathy and conduction defects v1.55 FKTN Rebecca Whittington commented on gene: FKTN: Cardiomyopathy, dilated, 1X OMIM#611615; Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, OMIM#253800; Muscular dystrophy-dystroglycanopathy (congenital without mental retardation), type B, OMIM#613152; Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, OMIM#611588.
Dilated Cardiomyopathy and conduction defects v1.54 FKTN Rebecca Whittington commented on gene: FKTN: HGMD: 4 variants 3 x DM but older literature.
Dilated Cardiomyopathy and conduction defects v1.53 FKTN Rebecca Whittington reviewed gene: FKTN: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal; Current diagnostic: yes
Dilated Cardiomyopathy and conduction defects v1.47 FKTN Ellen McDonagh Source South West GLH was added to FKTN.
Dilated Cardiomyopathy and conduction defects v1.46 FKTN Ellen McDonagh reviewed gene: FKTN: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Dilated Cardiomyopathy and conduction defects v1.45 FKTN Ellen McDonagh Source London South GLH was added to FKTN.
Dilated Cardiomyopathy and conduction defects v1.40 FKTN Oxford Medical Genetics Laboratory edited their review of gene: FKTN: Added comment: Not fully reviewed however doesn't appear to be associated with primary non-syndromic teen/adult onset DCM.; Changed rating: RED
Dilated Cardiomyopathy and conduction defects v1.39 FKTN Ellen McDonagh Source Wessex and West Midlands GLH was added to FKTN.
Rating Changed from Green List (high evidence) to Green List (high evidence)