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Inherited renal cancer v1.22 | SDHB | Arina Puzriakova Phenotypes for gene: SDHB were changed from Paragangliomas 4, OMIM:115310; Renal cell carcinoma (disease), MONDO:0005086 to Paragangliomas 4, OMIM:115310; Pheochromocytoma, OMIM:171300; Paraganglioma and gastric stromal sarcoma, OMIM:606864 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v1.10 | SDHB | Arina Puzriakova Added comment: Comment on phenotypes: This gene is also associated with Gastrointestinal stromal tumor (MIM# 6067640; Paraganglioma and gastric stromal sarcoma (MIM# 606864); Pheochromocytoma (MIM# 171300) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v1.10 | SDHB | Arina Puzriakova Phenotypes for gene: SDHB were changed from Cowden syndrome 2; Gastrointestinal stromal tumor; Paraganglioma and gastric stromal sarcoma; Paragangliomas 4; Pheochromocytoma. to Paragangliomas 4, OMIM:115310; Renal cell carcinoma (disease), MONDO:0005086 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v0.44 | SDHB | Rebecca Foulger Publications for gene: SDHB were set to PMID: 27899189 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v0.38 | SDHB | Ivone Leong commented on gene: SDHB | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v0.12 | SDHB | Ivone Leong Classified gene: SDHB as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v0.12 | SDHB | Ivone Leong Gene: sdhb has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v0.3 | SDHB | Lara Hawkes reviewed gene: SDHB: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inherited renal cancer v0.2 | SDHB |
Ivone Leong Source Expert List was added to SDHB. Rating Changed from No List (delete) to Red List (low evidence) |
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Inherited renal cancer v0.1 | SDHB |
Rachel Robinson gene: SDHB was added gene: SDHB was added to Inherited renal cancer. Sources: UKGTN Mode of inheritance for gene: SDHB was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: SDHB were set to PMID: 27899189 Phenotypes for gene: SDHB were set to Cowden syndrome 2; Gastrointestinal stromal tumor; Paraganglioma and gastric stromal sarcoma; Paragangliomas 4; Pheochromocytoma. Penetrance for gene: SDHB were set to Complete Review for gene: SDHB was set to GREEN gene: SDHB was marked as current diagnostic Added comment: Sources: UKGTN |