Activity

Filter

Cancel
Date Panel Item Activity
10 actions
Inherited renal cancer v1.22 SDHB Arina Puzriakova Phenotypes for gene: SDHB were changed from Paragangliomas 4, OMIM:115310; Renal cell carcinoma (disease), MONDO:0005086 to Paragangliomas 4, OMIM:115310; Pheochromocytoma, OMIM:171300; Paraganglioma and gastric stromal sarcoma, OMIM:606864
Inherited renal cancer v1.10 SDHB Arina Puzriakova Added comment: Comment on phenotypes: This gene is also associated with Gastrointestinal stromal tumor (MIM# 6067640; Paraganglioma and gastric stromal sarcoma (MIM# 606864); Pheochromocytoma (MIM# 171300)
Inherited renal cancer v1.10 SDHB Arina Puzriakova Phenotypes for gene: SDHB were changed from Cowden syndrome 2; Gastrointestinal stromal tumor; Paraganglioma and gastric stromal sarcoma; Paragangliomas 4; Pheochromocytoma. to Paragangliomas 4, OMIM:115310; Renal cell carcinoma (disease), MONDO:0005086
Inherited renal cancer v0.44 SDHB Rebecca Foulger Publications for gene: SDHB were set to PMID: 27899189
Inherited renal cancer v0.38 SDHB Ivone Leong commented on gene: SDHB
Inherited renal cancer v0.12 SDHB Ivone Leong Classified gene: SDHB as Green List (high evidence)
Inherited renal cancer v0.12 SDHB Ivone Leong Gene: sdhb has been classified as Green List (High Evidence).
Inherited renal cancer v0.3 SDHB Lara Hawkes reviewed gene: SDHB: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Inherited renal cancer v0.2 SDHB Ivone Leong Source Expert List was added to SDHB.
Rating Changed from No List (delete) to Red List (low evidence)
Inherited renal cancer v0.1 SDHB Rachel Robinson gene: SDHB was added
gene: SDHB was added to Inherited renal cancer. Sources: UKGTN
Mode of inheritance for gene: SDHB was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: SDHB were set to PMID: 27899189
Phenotypes for gene: SDHB were set to Cowden syndrome 2; Gastrointestinal stromal tumor; Paraganglioma and gastric stromal sarcoma; Paragangliomas 4; Pheochromocytoma.
Penetrance for gene: SDHB were set to Complete
Review for gene: SDHB was set to GREEN
gene: SDHB was marked as current diagnostic
Added comment: Sources: UKGTN