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Familial melanoma v1.9 POT1 Arina Puzriakova Phenotypes for gene: POT1 were changed from Melanoma, cutaneous malignant, susceptibility to, 10, 615848 to Melanoma, cutaneous malignant, susceptibility to, 10, OMIM:615848
Familial melanoma v1.8 POT1 Arina Puzriakova Publications for gene: POT1 were set to 24686849; 24686846; 29523635; 30451293; 30586141; 32325837
Familial melanoma v1.7 POT1 Arina Puzriakova edited their review of gene: POT1: Changed publications: 24686849, 24686846, 29523635, 30451293, 30586141, 32325837, 32907878
Familial melanoma v1.7 POT1 Arina Puzriakova Tag for-review tag was added to gene: POT1.
Familial melanoma v1.7 POT1 Arina Puzriakova Phenotypes for gene: POT1 were changed from to Melanoma, cutaneous malignant, susceptibility to, 10, 615848
Familial melanoma v1.6 POT1 Arina Puzriakova Publications for gene: POT1 were set to
Familial melanoma v1.5 POT1 Arina Puzriakova Classified gene: POT1 as Amber List (moderate evidence)
Familial melanoma v1.5 POT1 Arina Puzriakova Added comment: Comment on list classification: Based on evidence provided by several publications, POT1 should be considered for a rating upgrade from Amber to Green, and therefore will be flagged for review at the date of next GMS panel update (added 'for-review' tag).
Familial melanoma v1.5 POT1 Arina Puzriakova Gene: pot1 has been classified as Amber List (Moderate Evidence).
Familial melanoma v1.4 POT1 Arina Puzriakova edited their review of gene: POT1: Changed rating: GREEN; Changed mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Familial melanoma v1.4 POT1 Arina Puzriakova reviewed gene: POT1: Rating: ; Mode of pathogenicity: None; Publications: 24686849, 24686846, 29523635, 30451293, 30586141, 32325837; Phenotypes: Melanoma, cutaneous malignant, susceptibility to, 10, 615848; Mode of inheritance: None
Familial melanoma v0.20 POT1 Ivone Leong Classified gene: POT1 as Amber List (moderate evidence)
Familial melanoma v0.20 POT1 Ivone Leong Added comment: Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber.
Familial melanoma v0.20 POT1 Ivone Leong Gene: pot1 has been classified as Amber List (Moderate Evidence).
Familial melanoma v0.18 POT1 Ivone Leong Classified gene: POT1 as Amber List (moderate evidence)
Familial melanoma v0.18 POT1 Ivone Leong Gene: pot1 has been classified as Amber List (Moderate Evidence).
Familial melanoma v0.16 POT1 Ivone Leong Mode of inheritance for gene: POT1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Familial melanoma v0.3 POT1 Rachel Robinson reviewed gene: POT1: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: ; Current diagnostic: yes
Familial melanoma v0.3 POT1 Lara Hawkes reviewed gene: POT1: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Familial melanoma v0.2 POT1 Ivone Leong gene: POT1 was added
gene: POT1 was added to Familial melanoma. Sources: Expert List,NHS GMS
Mode of inheritance for gene: POT1 was set to