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Possible mitochondrial disorder - nuclear genes v3.81 COX11 Sarah Leigh Classified gene: COX11 as Amber List (moderate evidence)
Possible mitochondrial disorder - nuclear genes v3.81 COX11 Sarah Leigh Added comment: Comment on list classification: There is enough evidence for this gene to be rated GREEN at the next major review.
Possible mitochondrial disorder - nuclear genes v3.81 COX11 Sarah Leigh Gene: cox11 has been classified as Amber List (Moderate Evidence).
Possible mitochondrial disorder - nuclear genes v3.80 COX11 Sarah Leigh Tag Q4_23_promote_green tag was added to gene: COX11.
Tag Q4_23_NHS_review tag was added to gene: COX11.
Possible mitochondrial disorder - nuclear genes v3.80 COX11 Sarah Leigh reviewed gene: COX11: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None
Possible mitochondrial disorder - nuclear genes v3.80 COX11 Sarah Leigh Mode of inheritance for gene: COX11 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal
Possible mitochondrial disorder - nuclear genes v3.79 COX11 Sarah Leigh Phenotypes for gene: COX11 were changed from Mitochondrial complex IV deficiency, nuclear type 23, OMIM:620275; Mitochondrial complex IV deficiency, nuclear type 23, MONDO:0859520 to Mitochondrial complex IV deficiency, nuclear type 23, OMIM:620275; Mitochondrial complex IV deficiency, nuclear type 23, MONDO:0859520
Possible mitochondrial disorder - nuclear genes v3.78 COX11 Sarah Leigh Publications for gene: COX11 were set to 36030551; 38068960
Possible mitochondrial disorder - nuclear genes v3.77 COX11 Sarah Leigh Publications for gene: COX11 were set to 36030551
Possible mitochondrial disorder - nuclear genes v3.76 COX11 Sarah Leigh Publications for gene: COX11 were set to
Possible mitochondrial disorder - nuclear genes v3.75 COX11 Sarah Leigh Mode of inheritance for gene: COX11 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal
Possible mitochondrial disorder - nuclear genes v3.74 COX11 Sarah Leigh Phenotypes for gene: COX11 were changed from No OMIM phenotype to Mitochondrial complex IV deficiency, nuclear type 23, OMIM:620275; Mitochondrial complex IV deficiency, nuclear type 23, MONDO:0859520
Possible mitochondrial disorder - nuclear genes v3.48 COX11 Hannah Knight reviewed gene: COX11: Rating: AMBER; Mode of pathogenicity: None; Publications: 36030551; Phenotypes: Mitochondrial complex IV deficiency, nuclear type 23; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Possible mitochondrial disorder - nuclear genes v0.148 COX11 Ellen McDonagh Marked gene: COX11 as ready
Possible mitochondrial disorder - nuclear genes v0.148 COX11 Ellen McDonagh Added comment: Comment when marking as ready: This gene should remain Amber due to the overall review and evidence assessment from the GMS mitochondrial specialist test group, submitted by Carl Fratter.
Possible mitochondrial disorder - nuclear genes v0.148 COX11 Ellen McDonagh Gene: cox11 has been classified as Amber List (Moderate Evidence).
Possible mitochondrial disorder - nuclear genes v0.134 COX11 Carl Fratter reviewed gene: COX11: Rating: AMBER; Mode of pathogenicity: ; Publications: no mito reports found; Phenotypes: No OMIM phenotype; Mode of inheritance: Unknown
Possible mitochondrial disorder - nuclear genes v0.89 COX11 Ellen McDonagh Classified gene: COX11 as Amber List (moderate evidence)
Possible mitochondrial disorder - nuclear genes v0.89 COX11 Ellen McDonagh Added comment: Comment on list classification: This gene has been demoted to Amber until further evidence is provided. This gene is not currently on the Mitochondrial disorders panel (code 112, Version 1.151) - further evidence needs to be submitted to support promoting this gene family member to Green.
Possible mitochondrial disorder - nuclear genes v0.89 COX11 Ellen McDonagh Gene: cox11 has been classified as Amber List (Moderate Evidence).
Possible mitochondrial disorder - nuclear genes v0.5 COX11 Ivone Leong reviewed gene: COX11: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: No OMIM phenotype; Mode of inheritance: Unknown
Possible mitochondrial disorder - nuclear genes v0.2 COX11 Ivone Leong gene: COX11 was added
gene: COX11 was added to Possible mitochondrial disorder - nuclear genes. Sources: Expert Review Green,NHS GMS
Mode of inheritance for gene: COX11 was set to Unknown
Phenotypes for gene: COX11 were set to No OMIM phenotype