| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Endocrine neoplasia v1.25 | TP53 | Ivone Leong Tag for-review was removed from gene: TP53. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.25 | TP53 | Ivone Leong changed review comment from: After NHSGenomic Medicine Service consideration, the rating of this gene has not been changed.; to: After NHS Genomic Medicine Service consideration, the rating of this gene has not been changed. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.25 | TP53 | Ivone Leong commented on gene: TP53: After NHSGenomic Medicine Service consideration, the rating of this gene has not been changed. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.14 | TP53 |
Ivone Leong changed review comment from: This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review; to: This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). No further evidence was provided. This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review |
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| Endocrine neoplasia v1.10 | TP53 | Ivone Leong Classified gene: TP53 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.10 | TP53 | Ivone Leong Gene: tp53 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.9 | TP53 |
Ivone Leong gene: TP53 was added gene: TP53 was added to Endocrine neoplasms. Sources: Expert Review for-review tags were added to gene: TP53. Mode of inheritance for gene: TP53 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: TP53 were set to Endocrine Cancer; Paragangliomas 1, with or without deafness, 168000; Pheochromocytoma, 171300; Carcinoid tumors, intestinal, 114900; Merkel cell carcinoma, somatic; Paraganglioma and gastric stromal sarcoma, 606864; Cowden syndrome 3, 615106 Review for gene: TP53 was set to AMBER Added comment: This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review |
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