| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Endocrine neoplasia v1.25 | VHL | Ivone Leong Tag for-review was removed from gene: VHL. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.25 | VHL | Ivone Leong commented on gene: VHL: The rating of this gene has been updated following NHS Genomic Medicine Service approval. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.24 | VHL |
Ivone Leong Source Expert Review Green was added to VHL. Rating Changed from Amber List (moderate evidence) to Green List (high evidence) |
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| Endocrine neoplasia v1.14 | VHL |
Ivone Leong changed review comment from: This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review; to: This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). No further evidence was provided. This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review |
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| Endocrine neoplasia v1.10 | VHL |
Ivone Leong changed review comment from: This gene was proposed to be added to this panel with Green by Soo-Mi Park (East Anglian Medical Genetics Service). This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review; to: This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review |
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| Endocrine neoplasia v1.8 | VHL | Ivone Leong Classified gene: VHL as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.8 | VHL | Ivone Leong Gene: vhl has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Endocrine neoplasia v1.7 | VHL |
Ivone Leong gene: VHL was added gene: VHL was added to Endocrine neoplasms. Sources: Expert Review for-review tags were added to gene: VHL. Mode of inheritance for gene: VHL was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: VHL were set to Endocrine Cancer; Paragangliomas 1, with or without deafness, 168000; Pheochromocytoma, 171300; Carcinoid tumors, intestinal, 114900; Merkel cell carcinoma, somatic; Paraganglioma and gastric stromal sarcoma, 606864; Cowden syndrome 3, 615106 Review for gene: VHL was set to AMBER Added comment: This gene was proposed to be added to this panel with Green by Soo-Mi Park (East Anglian Medical Genetics Service). This gene is Green on the Multiple endocrine tumours (Version 1.9) panel. This gene has been added as an Amber gene and will be given Green status pending decision by the GMS review panel. Sources: Expert Review |
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