ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif 13
OMIM: 604134, Gene2Phenotype

8 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 8 panels
Amber ADAMTS13 in Atypical haemolytic uraemic syndrome Level 3: Syndromes with prominent renal abnormalities Level 2: Renal and urinary tract disorders Version 3.3 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Renal superpanel - broad Renal superpanel - narrow	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Expert list Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150 Tags for-review to_be_confirmed_NHSE
Green ADAMTS13 in Inherited bleeding disorders Level 3: Haemostasis disorders Level 2: Haematological and immunological disorders Version 1.177	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Research Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150
Green ADAMTS13 in Cytopenias and congenital anaemias Level 3: Anaemias and red cell disorders Level 2: Haematological disorders Version 1.118	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Illumina TruGenome Clinical Sequencing Services Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150
Green ADAMTS13 in Vascular skin disorders Version 1.63 Latest signed off version: v1.3 (15 Oct 2020)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150
Green ADAMTS13 in Thrombophilia with a likely monogenic cause Version 2.5 Latest signed off version: v2.2 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH Wessex and West Midlands GLH NHS GMS Expert Review Green Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150
Amber ADAMTS13 in Bleeding and platelet disorders Version 3.9 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber North West GLH Yorkshire and North East GLH London South GLH NHS GMS Wessex and West Midlands GLH Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150 Tags Q4_23_NHS_review Q4_23_promote_green
Amber ADAMTS13 in Cytopenia - NOT Fanconi anaemia Version 3.32 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Expert review Amber NHS GMS North West GLH London South GLH Yorkshire and North East GLH Wessex and West Midlands GLH Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150
Green ADAMTS13 in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Thrombotic thrombocytopenic purpura, hereditary, OMIM:274150