ALOX12B

arachidonate 12-lipoxygenase, 12R type
OMIM: 603741, Gene2Phenotype

8 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 8 panels
Red ALOX12B in Familial cicatricial alopecia Level 3: Skin adnexa disorders Level 2: Dermatological disorders Version 1.5	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red Other Phenotypes Ichthyosis, congenital, autosomal recessive 2, 242100 Lamellar ichthyosis Some affected persons exhibit scarring alopecia
Green ALOX12B in Palmoplantar keratoderma and erythrokeratodermas Level 3: Keratodermas Level 2: Dermatological disorders Version 1.31	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other Phenotypes Ichthyosis, congenital, autosomal recessive 2, 242100 (includes palmoplantar keratoderma) Nonbullous congenital ichthyosiform erythroderma (NBCIE)
Green ALOX12B in Autosomal recessive congenital ichthyosis Level 3: Ichthyoses Level 2: Dermatological disorders Version 1.14	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green UKGTN Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Eligibility statement prior genetic testing Phenotypes Ichthyosis, congenital, autosomal recessive 2, 242100
Green ALOX12B in Ichthyosis and erythrokeratoderma Version 3.28 Latest signed off version: v3.2 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes congenital non-bullous ichthyosiform erythroderma, MONDO:0019306 Ichthyosis, congenital, autosomal recessive 2, 242100 (includes palmoplantar keratoderma)
Red ALOX12B in Ectodermal dysplasia Version 3.29 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red Phenotypes Some affected persons exhibit scarring alopecia Ichthyosis, congenital, autosomal recessive 2, 242100 Lamellar ichthyosis
Green ALOX12B in Palmoplantar keratodermas Version 3.25 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources London North GLH NHS GMS Expert Review Green Phenotypes Autosomal recessive congenital ichthyosis
Green ALOX12B in Fetal anomalies Version 3.157 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Expert list Phenotypes Ichthyosis, congenital, autosomal recessive 2, 242100
Green ALOX12B in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Ichthyosis, congenital, autosomal recessive 2, 242100