ANGPT2

angiopoietin 2
OMIM: 601922, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Amber ANGPT2 in Fetal hydrops

Level 3: Fetal disorders
Level 2: Dysmorphic and congenital abnormality syndromes
Version 1.95

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • Lymphatic malformation 10 OMIM:619369
  • lymphatic malformation 10 MONDO:0023662
Green ANGPT2 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 6.140
Latest signed off version: v6.0 (30 Apr 2025)

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • NHS GMS
  • Literature
Phenotypes
  • hydrops fetalis, MONDO:0015193
  • Lymphatic malformation 10, OMIM:619369
  • lymphatic malformation 10, MONDO:0023662
Red ANGPT2 in DDG2P


Version 6.424
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Red
    Phenotypes
    • ANGPT2-related non-immune hydrops fetalis
    Amber ANGPT2 in Primary lymphoedema


    Level 2: Cardiology
    Version 4.21
    Latest signed off version: v4.0 (30 Apr 2025)

    review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Amber
    • Literature
    Phenotypes
    • Lymphatic malformation 10 OMIM:619369
    • lymphatic malformation 10 MONDO:0023662