1. Genes and Genomic Entities
  2. BMP15

BMP15

bone morphogenetic protein 15
OMIM: 300247, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green BMP15 in Primary ovarian insufficiency

Level 3: Gonadal and sex development disorders
Level 2: Endocrine disorders
Version 1.68

review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Sources
  • Expert Review Green
  • Other
  • Illumina TruGenome Clinical Sequencing Services
  • Radboud University Medical Center, Nijmegen
  • Expert list
Phenotypes
  • premature ovarian failure
  • Ovarian dysgenesis 2,300510
  • Premature ovarian failure 4300510
  • Ovarian Dysgenesis
Red BMP15 in Intellectual disability - microarray and sequencing

Level 3: Neurodevelopmental disorders
Level 2: Neurology and neurodevelopmental disorders
Version 5.544
Latest signed off version: v5.0 (22 Mar 2023)

Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
    Sources
    • Expert Review Red
    Phenotypes
    • Ovarian dysgenesis 2 300510
    • Premature ovarian failure 4 300510