C4B

complement C4B (Chido blood group)
OMIM: 120820, Gene2Phenotype

2 panels

Panel	Reviews	Mode of inheritance	Details
Green C4B in COVID-19 research Level 2: Viral research Version 1.146	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 North West GLH Victorian Clinical Genetics Services Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green GRID V2.0 Phenotypes C4B deficiency, 614379 SLE, infections with encapsulated organisms , partial deficiency is common (either C4A or C4B) and appears to have a modest effect on host defense Complement Deficiencies SLE predisposition
Green C4B in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green GRID V2.0 Phenotypes C4B deficiency, 614379 SLE predisposition SLE, infections with encapsulated organisms , partial deficiency is common (either C4A or C4B) and appears to have a modest effect on host defense Complement Deficiencies

Panel

Reviews

Mode of inheritance

Details

Level 2: Viral research
Version 1.146

review

BIALLELIC, autosomal or pseudoautosomal

C4B deficiency, 614379
SLE, infections with encapsulated organisms , partial deficiency is common (either C4A or C4B) and appears to have a modest effect on host defense
Complement Deficiencies
SLE predisposition

Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review

BIALLELIC, autosomal or pseudoautosomal

C4B deficiency, 614379
SLE predisposition
SLE, infections with encapsulated organisms , partial deficiency is common (either C4A or C4B) and appears to have a modest effect on host defense
Complement Deficiencies