CASP8

caspase 8
OMIM: 601763, Gene2Phenotype

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Green CASP8 in COVID-19 research Level 2: Viral research Version 1.141	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH GOSH PID v.8.0 NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes Caspase-8 deficiency state Immunodeficiency due to CASP8 deficiency CEDS ?Autoimmune lymphoproliferative syndrome, type IIB, 607271 Diseases of Immune Dysregulation Caspase 8 deficiency Autoimmune lymphoproliferative syndrome (ALPS) Adenopathies, splenomegaly, bacterial and viral infections, hypogammaglobulinemia
Green CASP8 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.201 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes Caspase-8 deficiency state CEDS Immunodeficiency due to CASP8 deficiency Caspase 8 deficiency Autoimmune lymphoproliferative syndrome (ALPS) ?Autoimmune lymphoproliferative syndrome, type IIB, 607271 Adenopathies, splenomegaly, bacterial and viral infections, hypogammaglobulinemia Diseases of Immune Dysregulation
Amber CASP8 in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Amber Expert list Phenotypes ?Autoimmune lymphoproliferative syndrome, type IIB, 607271