CD27

CD27 molecule
OMIM: 186711, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green CD27 in COVID-19 research


Level 2: Viral research
Version 1.130

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • London North GLH
  • GOSH PID v.8.0
  • NHS GMS
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • North West GLH
  • ESID Registry 20171117
  • Combined B and T cell defect v1.12
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
  • GOSH PID v.8.0
  • Combined B and T cell defect v1.12
Phenotypes
  • Lymphoproliferative syndrome 2
  • Combined immunodeficiency
  • Diseases of Immune Dysregulation
  • Features triggered by EBV infection, HLH, aplastic anemia, low iNKT cells, lymphoma
  • Combined immunodeficiency with EBV-associated lymphoproliferation
  • CD27 deficiency

Green CD27 in Primary immunodeficiency


Version 2.573
Latest signed off version: v2.1 (24 Feb 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
  • GOSH PID v.8.0
  • Combined B and T cell defect v1.12
Phenotypes
  • Lymphoproliferative syndrome 2
  • Combined immunodeficiency with EBV-associated lymphoproliferation
  • Combined immunodeficiency
  • CD27 deficiency
  • Features triggered by EBV infection, HLH, aplastic anemia, low iNKT cells, lymphoma
  • Diseases of Immune Dysregulation

Green CD27 in Severe Paediatric Disorders


Version 1.127

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Lymphoproliferative syndrome 2, 615122